{"id":"W3120292785","doi":"10.3389/fcell.2020.611326","title":"Endomembrane Tension and Trafficking","year":2021,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Endomembrane system; Endosome; Endocytic cycle; Cell biology; Biology; Exocytosis; Lysosome; Membrane curvature; Endocytosis; Intracellular; Biochemistry; Golgi apparatus; Vesicle; Cell; Secretion; Membrane; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001351096,0.0002831903,0.0007564537,0.0001194181,0.00005627593,0.00001376247,0.00007798538,0.0005261615,0.00001121805],"category_scores_gemma":[0.00001107734,0.0002469803,0.00009816953,0.0000917934,0.00011453,0.000002189539,0.00009763064,0.0001690365,0.000001689599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002203685,"about_ca_system_score_gemma":0.0001249344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006349385,"about_ca_topic_score_gemma":0.00001282144,"domain_scores_codex":[0.9987495,0.00008348237,0.0003336218,0.0005596239,0.00003993771,0.0002338648],"domain_scores_gemma":[0.999731,0.00001315074,0.00007848016,0.00009606291,0.00001294809,0.00006837441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002196231,0.000043766,0.001269086,0.002221354,0.00008944931,0.00004924499,0.00008627894,1.434111e-7,0.009210773,0.000009714776,0.000515091,0.9864832],"study_design_scores_gemma":[0.0003597223,0.00005249698,0.00001845276,0.0005257649,0.00005920244,0.0001067087,0.0001267654,0.000002598638,0.0003855468,0.000009054048,0.9980375,0.0003162311],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002757456,0.9947401,0.001260139,0.000004084801,0.0004184679,0.0002219453,0.00001725129,0.00000613003,0.0005744356],"genre_scores_gemma":[0.0005306309,0.9883813,0.003486672,0.00003804626,0.00006432091,0.00002107788,0.007097611,0.00002305979,0.0003572682],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9975224,"threshold_uncertainty_score":0.9999983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01406532630080421,"score_gpt":0.2387833161255411,"score_spread":0.2247179898247369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}