{"id":"W3120319797","doi":"10.1101/2021.01.04.425196","title":"Aurora kinases promote mitotic progression and asymmetric cell division through activation of Polo kinase","year":2021,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Cell biology; Mitosis; Polo-like kinase; Biology; Asymmetric cell division; Spindle checkpoint; Cell division; Spindle apparatus; Kinase; Stem cell; Cell cycle; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007588226,0.0002309597,0.00009828461,0.0002075551,0.0001269851,0.000323128,0.00007870545,0.000141174,0.002151052],"category_scores_gemma":[0.0001046883,0.00009564612,0.0001054107,0.00007715626,0.000137578,0.0001735283,0.0002708699,0.0002673609,0.0005521623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002251798,"about_ca_system_score_gemma":0.0002042327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004347925,"about_ca_topic_score_gemma":0.0007086945,"domain_scores_codex":[0.9999379,0.000009295273,0.000004937855,0.00001314818,0.00001872159,0.00001601564],"domain_scores_gemma":[0.9999455,0.000005959474,0.00001679802,0.00000637331,0.00000717988,0.00001815927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000140118,0.00001166084,0.0004978855,0.00004132225,0.00000487339,0.0001004802,0.00001474872,0.000136924,0.9959012,0.0005840515,0.0001072839,0.002459512],"study_design_scores_gemma":[0.00002790452,0.00005843934,0.01196419,0.000009481982,0.000009571857,0.0002799871,0.0000307146,0.002096273,0.9790074,0.000475024,0.006037465,0.000003589778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837682,0.00250113,0.004232237,0.0002037487,0.00005753029,0.00001425375,0.0002969943,0.0002395544,0.008686319],"genre_scores_gemma":[0.9944972,0.0005045548,0.0008691236,0.00001413044,0.000009242169,0.000007308613,0.0001478709,0.00001626149,0.003934291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002151052,"threshold_uncertainty_score":0.00719595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009677712634803841,"score_gpt":0.2418714590630594,"score_spread":0.2321937464282556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}