{"id":"W3120355471","doi":"10.1136/annrheumdis-2020-eular.2053","title":"THU0396 IMPACT OF IXEKIZUMAB ON WORK PRODUCTIVITY IN PATIENTS WITH ANKYLOSING SPONDYLITIS: RESULTS FROM THE COAST-V AND COAST-W TRIALS AT 52 WEEKS","year":2020,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Memorial University of Newfoundland","funders":"Celgene; Gilead Sciences; Pfizer; Eli Lilly and Company","keywords":"Ixekizumab; Medicine; Ankylosing spondylitis; Adalimumab; Placebo; Work productivity; Internal medicine; Presenteeism; Absenteeism; Physical therapy; Productivity; Secukinumab; Disease; Psoriatic arthritis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00165613,0.001285749,0.003044925,0.0002859222,0.0003665204,0.001281349,0.0008200743,0.001484623,0.003531465],"category_scores_gemma":[0.001760146,0.0004155157,0.004095803,0.0004465978,0.0008338129,0.0009771941,0.0004077993,0.00347077,0.0007217114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007012439,"about_ca_system_score_gemma":0.0007952569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001807009,"about_ca_topic_score_gemma":0.003445903,"domain_scores_codex":[0.9992175,0.0003365865,0.00007253415,0.0001310434,0.00006362166,0.0001787292],"domain_scores_gemma":[0.9989049,0.0003164152,0.0003095476,0.000103342,0.00009089304,0.0002748247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8970604,0.003702817,0.004899205,0.002501829,0.007300501,0.0001027253,0.0001597211,0.001127756,0.003185318,0.0001896376,0.002564765,0.07720529],"study_design_scores_gemma":[0.7543895,0.1950909,0.0374728,0.0006802233,0.006502865,0.0002396985,0.0003152411,0.0008158329,0.001110539,0.0004196954,0.002881755,0.0000809114],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683671,0.02637344,0.0001712297,0.0008659722,0.0004143769,0.000255257,0.001224799,0.00004823162,0.00227958],"genre_scores_gemma":[0.9890725,0.006191934,0.0002979366,0.0006138769,0.000287169,0.0002751369,0.0009942875,0.00001522583,0.002251765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003531465,"threshold_uncertainty_score":0.01181388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06039700618445116,"score_gpt":0.3101545334643434,"score_spread":0.2497575272798922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}