{"id":"W3120424609","doi":"10.3390/ijms22010407","title":"Insulin-Like Growth Factor Binding Protein-3 Binds to Histone 3","year":2021,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba; University of Winnipeg","funders":"Manitoba Medical Service Foundation","keywords":"Insulin-like growth factor-binding protein; Chromatin immunoprecipitation; Western blot; Binding protein; Nuclear protein; Biology; Molecular biology; Histone; Chromatin; Histone H3; Transcription factor; Immunoprecipitation; Non-histone protein; Growth factor; Biochemistry; Gene expression; Insulin-like growth factor; Gene; Promoter; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009719405,0.0003945307,0.000238055,0.0002121953,0.0004702281,0.0002984523,0.0002381306,0.0003324753,0.004026377],"category_scores_gemma":[0.0001849705,0.0001661154,0.0008158914,0.0002311703,0.0002199031,0.0001488643,0.0003260038,0.0005100755,0.001429626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006182324,"about_ca_system_score_gemma":0.000340419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006138362,"about_ca_topic_score_gemma":0.005323515,"domain_scores_codex":[0.999833,0.00001643077,0.000007674904,0.00004789049,0.00004407547,0.00005096254],"domain_scores_gemma":[0.9998958,0.00001790817,0.0000221755,0.000009406537,0.00002249399,0.00003221953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001267038,0.00002250918,0.00123865,0.00007553616,0.00001758767,0.0001191909,0.00003024602,0.00003532104,0.9963362,0.00009446894,0.000162861,0.001740597],"study_design_scores_gemma":[0.00003633956,0.0003505672,0.09281782,0.00003816148,0.00005901307,0.001026624,0.0001718644,0.002054948,0.8897148,0.0003316607,0.01337404,0.00002414199],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9604083,0.007174613,0.02269398,0.0005618337,0.0002514189,0.00005412655,0.0008857888,0.0002542995,0.007715664],"genre_scores_gemma":[0.9804627,0.001742115,0.007665735,0.0005195444,0.00004771544,0.00002623947,0.001515822,0.0000439049,0.007976354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006138362,"threshold_uncertainty_score":0.01346958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02310204300753297,"score_gpt":0.3077041578291828,"score_spread":0.2846021148216498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}