{"id":"W3120541852","doi":"10.1111/and.13960","title":"Transcriptome modulation following administration of luteolin to bleomycin‐etoposide‐cisplatin chemotherapy on rat LC540 tumor Leydig cells","year":2021,"lang":"en","type":"article","venue":"Andrologia","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"Natural Sciences and Engineering Research Council of Canada; New Brunswick Innovation Foundation; Fondation de la recherche en santé du Nouveau-Brunswick; Beatrice Hunter Cancer Research Institute","keywords":"Bleomycin; Transcriptome; Etoposide; Cisplatin; Cancer research; Biology; Luteolin; Leydig cell; Downregulation and upregulation; Apoptosis; Testicular cancer; Chemotherapy; Pharmacology; Gene expression; Endocrinology; Gene; Biochemistry; Antioxidant; Genetics; Luteinizing hormone; Flavonoid; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006725809,0.0001355033,0.0002842669,0.0001334086,0.000111972,0.0002216115,0.00007985609,0.0001351614,0.00105287],"category_scores_gemma":[0.00007581477,0.00009250666,0.0002326755,0.0001743978,0.0001861833,0.0001157373,0.0001241605,0.0003052974,0.0002326003],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002156048,"about_ca_system_score_gemma":0.0002152386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007729624,"about_ca_topic_score_gemma":0.001172258,"domain_scores_codex":[0.9999279,0.00000987507,0.000003452684,0.00002337684,0.00001592529,0.00001944631],"domain_scores_gemma":[0.9999588,0.000008185162,0.00001063573,0.000003913253,0.000006977597,0.00001145893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002110045,0.00001167286,0.0002214516,0.00002958977,0.000003524839,0.00001863936,0.00001247716,0.00003305678,0.9987608,0.00001280765,0.00002834202,0.0006565764],"study_design_scores_gemma":[0.00002342054,0.0005317576,0.02749828,0.00001006757,0.00003894858,0.00009549753,0.0001010043,0.000714498,0.9683671,0.00002937145,0.002581547,0.00000859909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954158,0.001282354,0.001076533,0.00008357559,0.00003580009,0.00002154471,0.0009041232,0.00005168016,0.001128558],"genre_scores_gemma":[0.9930078,0.001035647,0.001230134,0.0001395755,0.00001214842,0.00006845492,0.001158715,0.00002263783,0.003324989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00105287,"threshold_uncertainty_score":0.003522158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009237073522677514,"score_gpt":0.2545459683999188,"score_spread":0.2453088948772413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}