{"id":"W3120541852","doi":"10.1111/and.13960","title":"Transcriptome modulation following administration of luteolin to bleomycin‐etoposide‐cisplatin chemotherapy on rat LC540 tumor Leydig cells","year":2021,"lang":"en","type":"article","venue":"Andrologia","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"Natural Sciences and Engineering Research Council of Canada; New Brunswick Innovation Foundation; Fondation de la recherche en santé du Nouveau-Brunswick; Beatrice Hunter Cancer Research Institute","keywords":"Bleomycin; Transcriptome; Etoposide; Cisplatin; Cancer research; Biology; Luteolin; Leydig cell; Downregulation and upregulation; Apoptosis; Testicular cancer; Chemotherapy; Pharmacology; Gene expression; Endocrinology; Gene; Biochemistry; Antioxidant; Genetics; Luteinizing hormone; Flavonoid; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001526068,0.0001643427,0.0002441163,0.00004681509,0.00005481064,0.000019646,0.0001039991,0.000145323,0.00004179049],"category_scores_gemma":[0.00004103972,0.0001639896,0.0001736662,0.0001361054,0.00002465015,0.000007079796,0.00001835711,0.00007979417,0.00000857811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001169042,"about_ca_system_score_gemma":0.0001326865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001512205,"about_ca_topic_score_gemma":0.00006242821,"domain_scores_codex":[0.9989231,0.000058111,0.0002793563,0.0003756718,0.0001476042,0.0002162199],"domain_scores_gemma":[0.9994224,0.00001379744,0.00008093027,0.0003092453,0.00009572232,0.00007789261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003731803,0.00007958784,0.000444539,0.00001384373,0.00004178372,0.0000016675,0.0001020758,0.0004587374,0.9915913,0.00009950963,0.004940141,0.001853614],"study_design_scores_gemma":[0.001008139,0.0005330971,0.003724074,0.0000176005,0.00002976681,0.00001090902,0.00004419414,0.00007405497,0.9256944,0.00006228595,0.06862463,0.0001768694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933023,0.000405218,0.001894713,0.0004317354,0.003074116,0.000219951,0.0000231328,0.00001457583,0.0006342041],"genre_scores_gemma":[0.9941489,0.0001301531,0.0009719277,0.001973266,0.001678165,0.00002136549,0.000127127,0.00002022379,0.0009289391],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06589694,"threshold_uncertainty_score":0.6687302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009237073522677514,"score_gpt":0.2545459683999188,"score_spread":0.2453088948772413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}