{"id":"W3120612324","doi":"10.1093/ofid/ofaa439.1204","title":"1018. Health Technology Assessment of New Long-Acting, Directly-Observed HIV Treatments in Canada: Impact of Real-World Adherence to Daily Oral Therapy on Treatment, Transmission and Cost-Effectiveness","year":2020,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"GlaxoSmithKline (Canada)","funders":"","keywords":"Medicine; Dosing; Clinical trial; Medication adherence; Transmission (telecommunications); Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008073107,0.0008597297,0.001186565,0.002410358,0.0008533547,0.003405516,0.00205646,0.001256138,0.006899328],"category_scores_gemma":[0.03841333,0.0005472049,0.004150735,0.004456307,0.0006874258,0.0008640742,0.001233563,0.001539285,0.0004145996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.08886449,"about_ca_system_score_gemma":0.1256843,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9779618,"about_ca_topic_score_gemma":0.9589781,"domain_scores_codex":[0.9883802,0.005404746,0.0008351041,0.0007568455,0.003830424,0.0007926205],"domain_scores_gemma":[0.9819099,0.006171326,0.002331121,0.000392868,0.007936001,0.00125891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006472745,0.001204599,0.4570793,0.01276732,0.01141731,0.0003743303,0.0004806868,0.2307642,0.0005577697,0.01836951,0.02148253,0.2390297],"study_design_scores_gemma":[0.003897967,0.002840177,0.5397245,0.006522101,0.007413126,0.0003513759,0.0008078894,0.4070353,0.001295852,0.004561445,0.02521597,0.0003343782],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6703154,0.07787275,0.02540579,0.01892194,0.0007585287,0.006204431,0.1432184,0.0004552711,0.05684741],"genre_scores_gemma":[0.9636777,0.009378588,0.01006894,0.0008327254,0.00007082993,0.0005869749,0.0123097,0.00002918223,0.003045332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08886449,"threshold_uncertainty_score":0.64476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1032341444853573,"score_gpt":0.4421689730830649,"score_spread":0.3389348285977076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}