{"id":"W3120771989","doi":"10.25251/skin.5.supp.16","title":"Bimekizumab versus Ustekinumab Efficacy Across Subgroups of Patients with Moderate to Severe Plaque Psoriasis: Results from the Multicenter, Randomized, Double-Blinded Phase 3 BE VIVID Trial","year":2021,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; McMaster University","funders":"","keywords":"Ustekinumab; Plaque psoriasis; Medicine; Double blinded; Psoriasis; Internal medicine; Randomized controlled trial; Multicenter study; Dermatology; Pathology; Placebo; Disease; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001446056,0.0004050346,0.001398187,0.00008884984,0.0003419107,0.00002481556,0.0006141192,0.0002322845,0.0002236323],"category_scores_gemma":[0.001258178,0.000183789,0.0003139418,0.000326564,0.0004527362,0.00009009501,0.0001070323,0.0005097665,0.00001740022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000941024,"about_ca_system_score_gemma":0.0002300442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002883804,"about_ca_topic_score_gemma":0.0003209525,"domain_scores_codex":[0.9959558,0.001486845,0.001426321,0.0003112929,0.0003648356,0.0004549244],"domain_scores_gemma":[0.9910256,0.006199824,0.001306662,0.0006624338,0.0007125935,0.00009288512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9717028,0.001230101,0.00001388004,0.000007458383,0.003598884,0.0002231501,0.0120563,0.0003144739,0.001400954,0.00001052643,0.0014254,0.008016095],"study_design_scores_gemma":[0.9710951,0.004536327,0.00007019562,0.0003320985,0.002732539,0.0004963829,0.002347856,0.00001153112,0.01608087,0.00002489837,0.002066207,0.0002060123],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888836,0.002205372,0.0001234,0.002646456,0.004096671,0.001379056,0.0005287122,0.0000152524,0.0001214901],"genre_scores_gemma":[0.9978814,0.0005807195,0.00009642528,0.0002450063,0.0005795952,0.00001449581,0.0002719466,0.00003458888,0.0002958776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01467991,"threshold_uncertainty_score":0.74947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03190225859256773,"score_gpt":0.2984405727850189,"score_spread":0.2665383141924512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}