{"id":"W3120829320","doi":"10.2147/ott.s242248","title":"Further Understanding of Urokinase Plasminogen Activator Overexpression in Urothelial Bladder Cancer Progression, Clinical Outcomes and Potential Therapeutic Targets","year":2021,"lang":"en","type":"review","venue":"OncoTargets and Therapy","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"European Association of Urology","keywords":"Medicine; Bladder cancer; Metastasis; Pathological; Angiogenesis; Cancer; Oncology; Disease; Tumor progression; Urokinase receptor; Plasminogen activator; Internal medicine; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003055558,0.0004404875,0.001146564,0.00008092545,0.00008041649,0.00003561537,0.0001457822,0.0005888689,0.00009925849],"category_scores_gemma":[0.00002451522,0.000301001,0.0003398407,0.00007546865,0.000131656,0.00001130047,0.0001497356,0.0002836881,5.313825e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002710759,"about_ca_system_score_gemma":0.0002986117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001754788,"about_ca_topic_score_gemma":0.000005015639,"domain_scores_codex":[0.9978783,0.0003451385,0.0006163701,0.0006579927,0.0002005074,0.0003016877],"domain_scores_gemma":[0.9990965,0.00004452535,0.0003851136,0.0003052806,0.00004206231,0.0001265118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004221778,0.0006317903,0.001417467,0.001267833,0.001312047,0.000045791,0.0001584331,6.290027e-7,0.03506389,0.0002226797,0.0004063663,0.9590509],"study_design_scores_gemma":[0.004105332,0.001107757,0.0001537684,0.007519255,0.0002834834,0.00003530215,0.0001396394,0.00001037665,0.02596326,0.000718263,0.9588637,0.001099862],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01157965,0.9870852,0.0001117297,0.00003736532,0.0002873904,0.0007490904,0.0001015622,0.000007470762,0.00004058587],"genre_scores_gemma":[0.01892558,0.9801157,0.0001444359,0.0001278922,0.0003317284,0.0001080816,0.0000927906,0.00007127398,0.0000824939],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9584574,"threshold_uncertainty_score":0.9999442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06068501049646511,"score_gpt":0.3768407434044141,"score_spread":0.316155732907949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}