{"id":"W3120829320","doi":"10.2147/ott.s242248","title":"Further Understanding of Urokinase Plasminogen Activator Overexpression in Urothelial Bladder Cancer Progression, Clinical Outcomes and Potential Therapeutic Targets","year":2021,"lang":"en","type":"review","venue":"OncoTargets and Therapy","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"European Association of Urology","keywords":"Medicine; Bladder cancer; Metastasis; Pathological; Angiogenesis; Cancer; Oncology; Disease; Tumor progression; Urokinase receptor; Plasminogen activator; Internal medicine; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00190982,0.0003820474,0.001350157,0.001984971,0.0001682576,0.001185407,0.0004498308,0.0008174291,0.002711577],"category_scores_gemma":[0.00271547,0.0001610271,0.001159813,0.00321902,0.000270149,0.001683565,0.0003326141,0.000744431,0.0004026067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007488214,"about_ca_system_score_gemma":0.002482445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001280016,"about_ca_topic_score_gemma":0.002023911,"domain_scores_codex":[0.9995716,0.000162475,0.00009099413,0.00005152267,0.00008422888,0.00003909323],"domain_scores_gemma":[0.9973146,0.00142273,0.000686054,0.00005538792,0.0004418397,0.00007929732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001453214,0.0004042141,0.03910505,0.1467532,0.001814255,0.002354269,0.0004682472,0.001367307,0.01851022,0.003397363,0.0132159,0.7711568],"study_design_scores_gemma":[0.0007943364,0.004346692,0.3229878,0.09323858,0.01675652,0.01650787,0.003502768,0.006247532,0.01455833,0.02149366,0.4992483,0.0003176108],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009604007,0.9862634,0.0005015698,0.002410151,0.0001341315,0.00002428288,0.0003075151,0.00001172286,0.0007432124],"genre_scores_gemma":[0.1154261,0.8783873,0.002370204,0.001402634,0.000903553,0.0001092935,0.0007649204,0.000005349174,0.0006305694],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002711577,"threshold_uncertainty_score":0.01010025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06068501049646511,"score_gpt":0.3768407434044141,"score_spread":0.316155732907949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}