{"id":"W3121303812","doi":"10.1371/journal.pgen.1008871","title":"Factors enforcing the species boundary between the human pathogens Cryptococcus neoformans and Cryptococcus deneoformans","year":2021,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"H2020 Marie Skłodowska-Curie Actions; National Institute of Allergy and Infectious Diseases; Horizon 2020; Instituto de Salud Carlos III; European Commission; European Regional Development Fund; Canadian Institute for Advanced Research; Horizon 2020 Framework Programme; Agència de Gestió d'Ajuts Universitaris i de Recerca; National Institutes of Health; National Institute of General Medical Sciences; Generalitat de Catalunya; Centres de Recerca de Catalunya","keywords":"Biology; Cryptococcus neoformans; Cryptococcus; MSH2; Genetics; Genetic recombination; Homologous recombination; DNA mismatch repair; Mitotic crossover; Meiosis; Recombination; DNA repair; DNA; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002808055,0.0002252451,0.0001960073,0.0003354496,0.000249509,0.0004434178,0.0001633066,0.0002953057,0.0008455258],"category_scores_gemma":[0.0006174275,0.0001236097,0.0001159733,0.0001574111,0.0002627692,0.0002499988,0.0004632138,0.0002872775,0.0001563329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003753622,"about_ca_system_score_gemma":0.0003507031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001627781,"about_ca_topic_score_gemma":0.002132919,"domain_scores_codex":[0.9995913,0.00007575144,0.00003789384,0.00008390184,0.0001105126,0.000100674],"domain_scores_gemma":[0.9995413,0.00009194217,0.0001932354,0.00004194704,0.00004604824,0.00008563865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009002268,0.00002227227,0.005715661,0.00003139259,0.000003702676,0.0001771959,0.00004993977,0.00004364148,0.9919112,0.0001586217,0.00002393507,0.001772542],"study_design_scores_gemma":[0.0000181273,0.0004439596,0.2186531,0.00003415466,0.00003165316,0.003451495,0.001023719,0.001078424,0.7687623,0.0004095435,0.006065987,0.00002753021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977261,0.0003946448,0.0007515406,0.00005235221,0.000007885112,0.00001880514,0.00007673277,0.00002087151,0.0009510553],"genre_scores_gemma":[0.9984011,0.00009783471,0.0009602379,0.00004892438,0.000002909121,0.000007044871,0.0001237994,0.000005520489,0.0003525987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001627781,"threshold_uncertainty_score":0.003236651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06746845350445208,"score_gpt":0.2867815175500081,"score_spread":0.219313064045556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}