{"id":"W3121469164","doi":"10.3389/fnut.2020.619216","title":"Mitochondrial Content, but Not Function, Is Altered With a Multimodal Resistance Training Protocol and Adequate Protein Intake in Leucine-Supplemented Pre/Frail Women","year":2021,"lang":"en","type":"article","venue":"Frontiers in Nutrition","topic":"Nutrition and Health in Aging","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal General Hospital; McGill University; Children's Hospital of Eastern Ontario; University of Ottawa; McGill University Health Centre","funders":"Canadian Institutes of Health Research; McGill University Health Centre","keywords":"Sarcopenia; Mitophagy; Mitochondrial biogenesis; Mitochondrion; Internal medicine; Mitochondrial permeability transition pore; Placebo; Leucine; Medicine; Endocrinology; Reactive oxygen species; Randomized controlled trial; Biology; Biochemistry; Apoptosis; Autophagy; Pathology; Programmed cell death; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000432325,0.0004542449,0.0007301985,0.0001543754,0.0002765668,0.0002028225,0.0001929107,0.000383163,0.00164957],"category_scores_gemma":[0.0005569978,0.0002067745,0.0003561088,0.0001341245,0.0002711647,0.0001305302,0.0002149812,0.0003385738,0.0002093457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000190636,"about_ca_system_score_gemma":0.000250556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008766138,"about_ca_topic_score_gemma":0.001330329,"domain_scores_codex":[0.9998852,0.00003624978,0.00001369467,0.00002744332,0.00001119625,0.00002617891],"domain_scores_gemma":[0.9997906,0.00003168968,0.00004802164,0.00001801128,0.00001696451,0.00009470413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6842115,0.02061529,0.03663995,0.0006119813,0.0006859051,0.0003290983,0.0004701536,0.0002705733,0.2036901,0.00003887744,0.0004263268,0.05201028],"study_design_scores_gemma":[0.02539534,0.5373019,0.4153644,0.00008507606,0.001177115,0.0003635396,0.0003908098,0.0007775099,0.01754818,0.00008776453,0.001469811,0.00003843594],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994292,0.0002775929,0.00006905013,0.00002325758,0.00001214,0.00004337938,0.00005642263,0.00000397433,0.00008500093],"genre_scores_gemma":[0.9985145,0.0002365216,0.0002555058,0.00008280872,0.00001931741,0.0002392106,0.0001338448,0.000002580208,0.0005157807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00164957,"threshold_uncertainty_score":0.005518317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04484578742704932,"score_gpt":0.295979244298508,"score_spread":0.2511334568714587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}