{"id":"W3121676279","doi":"10.1007/s40290-020-00370-9","title":"Drug Advertising Violations: A Longitudinal Trend Analysis of FDA Enforcement Letters from 2005 to 2019","year":2021,"lang":"en","type":"article","venue":"Pharmaceutical Medicine","topic":"Pharmaceutical industry and healthcare","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Work & Health; Public Health Ontario; McMaster University; University of Toronto","funders":"","keywords":"Enforcement; Revenue; Promotion (chess); Advertising; Business; Medical prescription; Food and drug administration; Prescription drug; Medicine; Marketing; Accounting; Environmental health; Pharmacology; Political science; Law","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001298411,0.0004555084,0.001120597,0.0005735376,0.0003012377,0.00001793996,0.0004218732,0.0003347309,0.03967651],"category_scores_gemma":[0.0005337452,0.0004201465,0.0003082138,0.002266324,0.0004546426,0.0001753233,0.0002367223,0.001811469,0.0001628782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002574085,"about_ca_system_score_gemma":0.0001637289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000377483,"about_ca_topic_score_gemma":0.0003153417,"domain_scores_codex":[0.9951549,0.0009377643,0.001303831,0.0008424413,0.0006805629,0.001080546],"domain_scores_gemma":[0.9953607,0.001864672,0.0002296065,0.0004764515,0.0002372104,0.001831385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003022682,0.001976968,0.2533089,0.0003637994,0.01314931,0.0009376516,0.005211807,0.01562321,0.5028029,0.006223158,0.1278541,0.06952544],"study_design_scores_gemma":[0.007985433,0.0002047681,0.05576181,0.000408288,0.01871317,0.00003494055,0.0009935467,0.05933492,0.1463907,0.0004100341,0.7086295,0.001132848],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8985046,0.009709667,0.002651814,0.0781854,0.00284863,0.0008525101,0.001031108,0.0001836743,0.006032663],"genre_scores_gemma":[0.966933,0.001051287,0.0004066799,0.02909243,0.0009680825,0.00005499114,0.0005980829,0.00003420274,0.0008612983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5807754,"threshold_uncertainty_score":0.9998251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3513951824707327,"score_gpt":0.5601475269582138,"score_spread":0.2087523444874811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}