{"id":"W3121743087","doi":"10.20944/preprints201810.0314.v1","title":"Comprehensive Analysis of Hepatitis B Virus Promoter Region Mutations","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Calgary; University of Lethbridge","funders":"","keywords":"cccDNA; Biology; Hepatitis B virus; Virology; Viral replication; Genome; Computational biology; Virus; Genetics; Gene; HBsAg","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005500008,0.0002365547,0.0003885031,0.001815374,0.0003249698,0.0004403233,0.0001804848,0.0002888085,0.001826235],"category_scores_gemma":[0.001451166,0.000157985,0.0005476199,0.001849868,0.0001360579,0.0002004836,0.0002756991,0.0003502743,0.001104765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001844072,"about_ca_system_score_gemma":0.0004382787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001859455,"about_ca_topic_score_gemma":0.002997511,"domain_scores_codex":[0.9996594,0.00003913213,0.00004050935,0.0001127552,0.0001129132,0.00003520779],"domain_scores_gemma":[0.9992237,0.0002325618,0.0002085367,0.00006210097,0.0001787288,0.00009440089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001927329,0.0002460603,0.391039,0.001705844,0.0005324502,0.00245207,0.001129204,0.004016932,0.438253,0.0009713857,0.007335426,0.1503914],"study_design_scores_gemma":[0.00007431624,0.0007036466,0.7955425,0.0003884711,0.000882435,0.008513772,0.0007258232,0.01040084,0.1035401,0.001134412,0.07798786,0.0001058116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9425364,0.005161393,0.006580673,0.0001490029,0.00004342881,0.00007887376,0.04237656,0.0004516109,0.002622008],"genre_scores_gemma":[0.890369,0.002436654,0.02254484,0.0002068344,0.0000349933,0.00009146738,0.08195703,0.0002243599,0.002134818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001859455,"threshold_uncertainty_score":0.006109357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1677130601831456,"score_gpt":0.3835200305699414,"score_spread":0.2158069703867958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}