{"id":"W3121861532","doi":"10.21203/rs.3.rs-40718/v1","title":"Mature and immature β-cells both contribute to islet function and insulin release","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Alberta","keywords":"Islet; Insulin; Function (biology); Cell biology; Chemistry; Endocrinology; Internal medicine; Biology; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001710749,0.0003581549,0.0003054986,0.0002189603,0.0001127486,0.0007651213,0.0001240651,0.0002386181,0.002767014],"category_scores_gemma":[0.0001923076,0.0001023308,0.0001589239,0.0001917289,0.0002681367,0.000332345,0.0003312679,0.0007761843,0.0008237059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001586312,"about_ca_system_score_gemma":0.0001229127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001098537,"about_ca_topic_score_gemma":0.0001153983,"domain_scores_codex":[0.999905,0.00001193706,0.000005195554,0.00002524474,0.00003143176,0.00002115897],"domain_scores_gemma":[0.9998168,0.00003452929,0.00004487356,0.00002239654,0.00002311822,0.00005828104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001582635,0.0000189656,0.001110564,0.00003156504,0.000005446805,0.0001012517,0.00001634672,0.00008345374,0.9934301,0.0005602405,0.0001215844,0.004362347],"study_design_scores_gemma":[0.00003731064,0.0002848881,0.04564913,0.00001761539,0.00003162231,0.0009925106,0.000131342,0.003394731,0.9332516,0.003844108,0.01235196,0.00001317373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9684715,0.004282514,0.02044386,0.0004691073,0.0001490902,0.00001708456,0.0007881486,0.0002758213,0.005102872],"genre_scores_gemma":[0.9781305,0.001865353,0.008646487,0.0001564424,0.00008734287,0.00002046936,0.001035381,0.00008680412,0.009971246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002767014,"threshold_uncertainty_score":0.009256601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03298924345747232,"score_gpt":0.3373891383861827,"score_spread":0.3043998949287104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}