{"id":"W3122190074","doi":"10.3389/fcell.2021.630645","title":"Mesenchymal Stromal Cells Promote Retinal Vascular Repair by Modulating Sema3E and IL-17A in a Model of Ischemic Retinopathy","year":2021,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; McGill University; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Retinopathy of prematurity; Mesenchymal stem cell; Semaphorin; Retinal; Retina; Medicine; Angiogenesis; Retinopathy; Neurogenesis; Ischemia; Pathology; Cancer research; Ophthalmology; Biology; Cell biology; Neuroscience; Internal medicine; Endocrinology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000226059,0.0003961707,0.0003967663,0.0004055116,0.0001366753,0.000231638,0.0001687425,0.0002995952,0.001085868],"category_scores_gemma":[0.00008753237,0.0001400893,0.0003678591,0.0002079332,0.0003054293,0.000215103,0.0001669195,0.001197087,0.0002167047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001883201,"about_ca_system_score_gemma":0.0003751631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000653633,"about_ca_topic_score_gemma":0.0009483977,"domain_scores_codex":[0.9997883,0.00003853516,0.00002740891,0.00002678351,0.00005690496,0.00006212037],"domain_scores_gemma":[0.9998816,0.00001137507,0.00003087805,0.00001071352,0.00001078635,0.00005461766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008689901,0.0003288579,0.0001091011,0.00008203404,0.00001116794,0.00008385489,0.00003625583,0.00008211184,0.9958093,0.0001691525,0.00008480679,0.002334333],"study_design_scores_gemma":[0.0001329462,0.00239595,0.002053754,0.00001321432,0.00004500466,0.0001295627,0.00005372665,0.0009356053,0.9919207,0.00009857681,0.002215242,0.000005647264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925569,0.002803772,0.001928852,0.000263146,0.0001478801,0.00005916927,0.0002674057,0.0001725571,0.001800114],"genre_scores_gemma":[0.9916474,0.002309965,0.002523904,0.0001291742,0.00005601337,0.0001006259,0.0002632676,0.0000220466,0.002947693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001085868,"threshold_uncertainty_score":0.003632605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01372901056264232,"score_gpt":0.2142521302389557,"score_spread":0.2005231196763133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}