{"id":"W3122264888","doi":"10.20944/preprints202001.0077.v1","title":"The Role of Immune and Oxidative Pathways in Menstrual-Cycle Associated Depressive, Physio-Somatic, Breast and Anxiety Symptoms: Modulation by Sex Hormones","year":2020,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Menstrual Health and Disorders","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Faculty of Medicine, Chulalongkorn University; Chulalongkorn University","keywords":"Arylesterase; Paraoxonase; Internal medicine; Endocrinology; Malondialdehyde; Oxidative stress; Chemistry; Antioxidant; Hormone; Menstrual cycle; PON1; Estrogen; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004786001,0.0003431956,0.0007410277,0.00007448022,0.0001417899,0.00001714608,0.0001674809,0.0003210756,0.00002601108],"category_scores_gemma":[0.0003512671,0.0002854147,0.0000911627,0.0001551766,0.00021199,0.00008703478,0.0007895153,0.0006507655,0.000008593266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000955315,"about_ca_system_score_gemma":0.0001594698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008065103,"about_ca_topic_score_gemma":0.00002352366,"domain_scores_codex":[0.9975401,0.0002379105,0.0007831495,0.0007015762,0.000381067,0.000356262],"domain_scores_gemma":[0.998239,0.0001840094,0.0006417152,0.0005650527,0.0001379094,0.0002322862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003217841,0.000238329,0.851492,0.0006512312,0.0002232576,0.00000277973,0.004523215,0.00004865974,0.1243612,0.00007736993,0.000009729495,0.01805043],"study_design_scores_gemma":[0.001789541,0.00006331445,0.9550025,0.0004575572,0.00009243206,0.00001153808,0.001701426,0.01039713,0.02492135,0.005302717,0.00003314533,0.0002272922],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948676,0.001806446,0.0000107978,0.0003902928,0.00005753887,0.001268825,0.0001626625,0.00006300386,0.001372878],"genre_scores_gemma":[0.997496,0.00195624,0.00004455405,0.00005647556,0.00002710493,0.0001303559,0.000216643,0.00003511312,0.00003753365],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1035106,"threshold_uncertainty_score":0.9999598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02962591858689994,"score_gpt":0.2964684390804753,"score_spread":0.2668425204935754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}