{"id":"W3122277353","doi":"10.3389/fneur.2020.573095","title":"The Spatial and Cell-Type Distribution of SARS-CoV-2 Receptor ACE2 in the Human and Mouse Brains","year":2021,"lang":"en","type":"article","venue":"Frontiers in Neurology","topic":"Long-Term Effects of COVID-19","field":"Medicine","cited_by":540,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Zhejiang Chinese Medical University; Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"Olfactory bulb; Biology; Human brain; Neuroscience; Hippocampal formation; Cell type; Hippocampus; Angiotensin-converting enzyme 2; Thalamus; Choroid plexus; Central nervous system; Cell; Pathology; Medicine; Coronavirus disease 2019 (COVID-19); Disease; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000355905,0.00009648826,0.000226529,0.00004982463,0.00006513544,0.00001267322,0.0001031718,0.0001170989,0.000001915556],"category_scores_gemma":[0.0006554727,0.00006578145,0.00002395908,0.0001434058,0.0002921671,0.00003221212,0.00007714099,0.0003108781,6.359351e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001897746,"about_ca_system_score_gemma":0.00005710434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001049505,"about_ca_topic_score_gemma":0.0002950877,"domain_scores_codex":[0.9988834,0.000394884,0.0002032025,0.0002192441,0.0001074376,0.0001918377],"domain_scores_gemma":[0.9992505,0.0003570424,0.00006924693,0.0002667787,0.00003107363,0.00002540172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008967467,0.0001715583,0.7658552,0.0001633066,0.00002457887,0.0002459267,0.001051079,0.000005438087,0.1934344,0.0003339928,0.03599092,0.00182692],"study_design_scores_gemma":[0.007984416,0.002749839,0.7950125,0.00004312674,0.0001084663,0.0001823933,0.0003454871,0.001564377,0.1369891,0.001899841,0.05284212,0.0002783551],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866799,0.0006196091,0.0001931879,0.01167528,0.0003991377,0.0003368898,0.00001061867,0.000008799547,0.00007665151],"genre_scores_gemma":[0.9969934,0.0002745165,0.00006612696,0.002506653,0.00005877783,0.00001017888,0.00003826598,0.00001019783,0.00004189827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0564453,"threshold_uncertainty_score":0.2682489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01251557304328707,"score_gpt":0.279263411412405,"score_spread":0.2667478383691179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}