{"id":"W3122391308","doi":"10.1128/iai.00810-20","title":"A SNP in the Cache 1 Signaling Domain of Diguanylate Cyclase STM1987 Leads to Increased <i>In Vivo</i> Fitness of Invasive <i>Salmonella</i> Strains","year":2021,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Salmonella and Campylobacter epidemiology","field":"Agricultural and Biological Sciences","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Regina; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Salmonella; Single-nucleotide polymorphism; SNP; Microbiology; In vivo; Virology; Bloodstream infection; Genotype; Genetics; Bacteria; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002000575,0.0004552671,0.0002324626,0.0002935651,0.0002261224,0.0002516897,0.0003115617,0.0007682263,0.00549983],"category_scores_gemma":[0.0003260488,0.0002304544,0.0004408615,0.000183925,0.0003896603,0.00008060633,0.000273604,0.0006752479,0.0006027322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002092597,"about_ca_system_score_gemma":0.0002321412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001836042,"about_ca_topic_score_gemma":0.002009457,"domain_scores_codex":[0.9997779,0.00007117788,0.00002068909,0.00004360301,0.00003317899,0.00005355457],"domain_scores_gemma":[0.9995964,0.0001392016,0.00009996944,0.00002937829,0.00001375012,0.0001213356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002803718,0.0005760725,0.005147677,0.00007010605,0.00009321101,0.001531375,0.00007219679,0.0004892038,0.9862723,0.0003547735,0.0006179304,0.001971267],"study_design_scores_gemma":[0.001139753,0.008019072,0.3609428,0.0001621501,0.0004294669,0.008847181,0.0007569304,0.01534473,0.5968108,0.00106703,0.006332076,0.0001480683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980482,0.00007613921,0.0004641135,0.00009673044,0.00005041012,0.00001377961,0.0004659562,0.00003561593,0.0007491106],"genre_scores_gemma":[0.998071,0.00005826222,0.0003137278,0.0001060551,0.00001174912,0.0000108792,0.0004689144,0.0000244564,0.000934947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00549983,"threshold_uncertainty_score":0.01839882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03369630227701088,"score_gpt":0.2598659791113425,"score_spread":0.2261696768343316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}