{"id":"W3122741683","doi":"10.1093/toxsci/kfab012","title":"Elucidation of the Effects of Bisphenol A and Structural Analogs on Germ and Steroidogenic Cells Using Single Cell High-Content Imaging","year":2021,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Viability assay; Oxidative stress; Cytotoxic T cell; Chemistry; Cell culture; Bisphenol A; Cell; Leydig cell; Mitochondrion; Bisphenol S; Cell biology; Andrology; Biochemistry; Biology; In vitro; Hormone; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002090168,0.0003217713,0.0002119731,0.000263608,0.0002172122,0.0003306195,0.0002375916,0.0004690898,0.000981027],"category_scores_gemma":[0.0001836071,0.000167337,0.0002705808,0.0002116657,0.0002515194,0.0003451472,0.0002059239,0.0005156086,0.0003147091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00029432,"about_ca_system_score_gemma":0.0002271291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001672884,"about_ca_topic_score_gemma":0.002279925,"domain_scores_codex":[0.9998393,0.00001811728,0.00001084952,0.00004594435,0.00005625216,0.00002950354],"domain_scores_gemma":[0.9998481,0.00003668377,0.00003497373,0.00001654846,0.0000443541,0.00001934571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002477929,0.000007348751,0.0001731051,0.00003304565,0.000002929466,0.00002288837,0.00001449696,0.00005596222,0.9987094,0.00004459234,0.00001802563,0.0008933809],"study_design_scores_gemma":[0.000002369496,0.0001025569,0.003727673,0.000003629959,0.000008957456,0.00007322925,0.00004552999,0.0006940142,0.9936514,0.00004087499,0.001645876,0.000003809229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9676467,0.002740699,0.02476205,0.000242734,0.00006333876,0.00006312168,0.001098958,0.0001993764,0.003183036],"genre_scores_gemma":[0.9572156,0.003540911,0.03280447,0.0002645887,0.00002147159,0.0001450611,0.0009881415,0.00008740801,0.004932339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001672884,"threshold_uncertainty_score":0.003326237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02043745746004178,"score_gpt":0.2864895792297368,"score_spread":0.2660521217696951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}