{"id":"W3122778939","doi":"10.20944/preprints201904.0155.v1","title":"Rho GTPases – Emerging Regulators of Glucose Homeostasis and Metabolic Health","year":2019,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"H. Lundbeck A/S; Novo Nordisk Fonden; Novo Nordisk; Lundbeckfonden","keywords":"GTPase; Glucose homeostasis; Cell biology; Actin cytoskeleton; Biology; Guanine nucleotide exchange factor; Insulin; Cytoskeleton; Endocrinology; Cell; Biochemistry; Insulin resistance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006050558,0.0007420545,0.0006317177,0.000927351,0.000382558,0.002444651,0.0003034374,0.0009906046,0.008650145],"category_scores_gemma":[0.0007592812,0.0001913209,0.0003263679,0.001108053,0.0006514362,0.001209511,0.0007716211,0.001626068,0.006128506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006977245,"about_ca_system_score_gemma":0.0009670666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003215929,"about_ca_topic_score_gemma":0.0003262706,"domain_scores_codex":[0.9997389,0.00004891677,0.00001269535,0.0000505474,0.0001093918,0.00003946563],"domain_scores_gemma":[0.9997591,0.00006185791,0.00004714162,0.00002278383,0.00005805539,0.00005095576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0004905134,0.0000473302,0.001928358,0.00562891,0.0001538497,0.001802476,0.0005109054,0.001633729,0.04470553,0.2015745,0.1810241,0.5604998],"study_design_scores_gemma":[0.00002518212,0.00003492702,0.002573866,0.0004478682,0.00005553188,0.00165286,0.0001921252,0.0009037631,0.0113968,0.04492079,0.9377682,0.00002806184],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01297471,0.886224,0.01788113,0.01601989,0.0051604,0.00004948197,0.002371981,0.001495086,0.05782344],"genre_scores_gemma":[0.1297025,0.7819245,0.01117443,0.001805943,0.009300613,0.00009910538,0.004999831,0.0005278322,0.06046526],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008650145,"threshold_uncertainty_score":0.02893764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06298820263768934,"score_gpt":0.343686867212238,"score_spread":0.2806986645745487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}