{"id":"W3122794892","doi":"10.1002/cbic.202000835","title":"Recent Advances of DNA Tetrahedra for Therapeutic Delivery and Biosensing","year":2021,"lang":"en","type":"review","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"","keywords":"Nucleic acid; Oligonucleotide; Nanotechnology; DNA; Endocytosis; Computational biology; Transfection; Biosensor; Drug delivery; Chemistry; Biology; Biophysics; Cell; Materials science; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001704019,0.0004038636,0.001127899,0.00008078333,0.00006473345,0.00002227636,0.000155851,0.0004732204,0.000001159582],"category_scores_gemma":[0.0001037454,0.0003363072,0.000494045,0.000209613,0.0001884885,0.000003517467,0.0001305899,0.000117976,2.760944e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002444017,"about_ca_system_score_gemma":0.000152139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":4.331821e-7,"about_ca_topic_score_gemma":0.000002216018,"domain_scores_codex":[0.9984276,0.00005302659,0.0004872376,0.0006644186,0.0001100227,0.0002576689],"domain_scores_gemma":[0.9987509,0.00005621471,0.0003882384,0.0004836185,0.0002538023,0.00006728371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000009558225,0.00003926082,5.915103e-7,0.002548311,0.0002482563,0.00000137013,0.000003350173,2.414883e-8,0.05217285,0.00001083916,0.0002144204,0.9447511],"study_design_scores_gemma":[0.00007324507,0.00006200405,7.876351e-8,0.001149217,0.000361572,0.00002337754,0.00001725576,7.263548e-7,0.4521849,0.00001409087,0.5458965,0.0002169778],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000530457,0.9985398,0.0002486208,0.00002155998,0.000075371,0.0003600079,0.00007952515,0.0000231848,0.0001214503],"genre_scores_gemma":[0.000953085,0.9936375,0.004170347,0.00005859187,0.0001955786,0.00002200223,0.0007348339,0.00005677365,0.0001712568],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9445342,"threshold_uncertainty_score":0.9999089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03425399016615924,"score_gpt":0.337534509290911,"score_spread":0.3032805191247517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}