{"id":"W3122842350","doi":"10.3389/fphys.2021.629222","title":"From Congenital Disorders of Fat Malabsorption to Understanding Intra-Enterocyte Mechanisms Behind Chylomicron Assembly and Secretion","year":2021,"lang":"en","type":"review","venue":"Frontiers in Physiology","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Chylomicron; Enterocyte; Malabsorption; Secretion; Biology; Digestion (alchemy); Bioinformatics; Medicine; Endocrinology; Chemistry; Very low-density lipoprotein; Lipoprotein; Small intestine; Cholesterol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004465854,0.0007761905,0.0008979385,0.001921656,0.000213048,0.000754611,0.0006729394,0.0009662018,0.003428356],"category_scores_gemma":[0.0006927219,0.0001948704,0.0003981167,0.001447655,0.0006857112,0.00143228,0.0008602844,0.001867601,0.001912442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006336684,"about_ca_system_score_gemma":0.0009132891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006443553,"about_ca_topic_score_gemma":0.0007347272,"domain_scores_codex":[0.9998592,0.00002430728,0.00002324102,0.00002840433,0.0000495965,0.00001521476],"domain_scores_gemma":[0.9997198,0.0001365569,0.00003169752,0.00001073434,0.00006637578,0.00003481219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001710073,0.00006324943,0.0002813799,0.01933203,0.000102709,0.0006449344,0.0001042046,0.0004578039,0.004229377,0.01188089,0.03557482,0.9271575],"study_design_scores_gemma":[0.00001277856,0.00007847777,0.0009670188,0.003840035,0.00006131862,0.002265921,0.00006634849,0.00007570915,0.000776724,0.005058394,0.9867795,0.00001774202],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001283776,0.9976916,0.0002549245,0.0005203612,0.0002956631,0.000002782315,0.00001836619,0.00001335724,0.001074529],"genre_scores_gemma":[0.0007110402,0.9982089,0.000159509,0.000209448,0.0002555507,0.000003365631,0.00002907284,0.000001755729,0.0004213957],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003428356,"threshold_uncertainty_score":0.01146907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02674174239307614,"score_gpt":0.2863076471655148,"score_spread":0.2595659047724386,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}