{"id":"W3122934837","doi":"10.1007/s00125-020-05371-6","title":"The discovery of insulin in Toronto: beginning a 100 year journey of research and clinical achievement","year":2021,"lang":"en","type":"review","venue":"Diabetologia","topic":"Diabetes Management and Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"","keywords":"Insulin; Medicine; History; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002120048,0.001068996,0.001980199,0.001851165,0.0006523438,0.002871374,0.0009847197,0.003048267,0.004796548],"category_scores_gemma":[0.002699698,0.0003760553,0.0007941868,0.002838933,0.001643069,0.002838543,0.001889602,0.005610111,0.001573941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004759119,"about_ca_system_score_gemma":0.008047266,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01644714,"about_ca_topic_score_gemma":0.04478763,"domain_scores_codex":[0.9992762,0.0001599138,0.00008638748,0.00007890417,0.0002790628,0.000119514],"domain_scores_gemma":[0.9982333,0.0007726809,0.0001822362,0.00003912251,0.0004220926,0.0003505731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003555737,0.00006003906,0.000430103,0.02118765,0.0001593278,0.0003972887,0.0003184209,0.0002554283,0.001021206,0.01405501,0.2346904,0.7270696],"study_design_scores_gemma":[0.00002752338,0.000062349,0.0006296926,0.005176604,0.00007819988,0.0002823174,0.0001410367,0.00003893508,0.0001095418,0.001722209,0.991712,0.00001960596],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000041335,0.9962768,0.00002663357,0.002404176,0.0008530419,9.443249e-7,0.00001092108,0.000004289886,0.0003818463],"genre_scores_gemma":[0.000605843,0.9959984,0.00009739173,0.001827999,0.000858115,0.000002258223,0.00002539264,0.000002264497,0.0005823587],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9835529,"threshold_uncertainty_score":0.03452998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1999686055489664,"score_gpt":0.5136991580728767,"score_spread":0.3137305525239102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}