{"id":"W3123050006","doi":"10.3390/cancers13030410","title":"Specific Inhibition of HIF Activity: Can Peptides Lead the Way?","year":2021,"lang":"en","type":"review","venue":"Cancers","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Lead (geology); Chemistry; Computational biology; Biochemical engineering; Biology; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001430076,0.000293007,0.0008118707,0.00004796671,0.00007596651,0.00002374311,0.0002020876,0.0002797226,0.00005249054],"category_scores_gemma":[0.00003286724,0.0002210552,0.0005393287,0.0002121003,0.0001953279,0.000002459509,0.0001001091,0.0002379085,0.000004634996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002088081,"about_ca_system_score_gemma":0.001508524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001988263,"about_ca_topic_score_gemma":0.0002979705,"domain_scores_codex":[0.9987414,0.0001249723,0.0002774124,0.0004468102,0.0001619277,0.0002475112],"domain_scores_gemma":[0.9989173,0.00002128039,0.0002981716,0.0006117214,0.00009161581,0.00005994591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000008674132,0.000007910191,2.845107e-7,0.001404546,0.000162446,0.000001645019,0.00003568989,0.000005266557,0.008431329,0.00005630185,0.03441335,0.9554725],"study_design_scores_gemma":[0.0001371298,0.00003477685,0.000001906773,0.001423587,0.0002442074,0.00001721834,0.00005920159,3.677301e-7,0.007107033,0.000005915617,0.9907324,0.0002362696],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005791408,0.9955284,0.00003553881,0.0000378346,0.001760446,0.0003394948,0.0002297119,0.000006627449,0.001482826],"genre_scores_gemma":[0.000556224,0.9942568,0.00003490166,0.00007203397,0.003119545,0.0001005149,0.0003367061,0.00004889282,0.001474373],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.956319,"threshold_uncertainty_score":0.9014368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03900702853861635,"score_gpt":0.2980397907480181,"score_spread":0.2590327622094017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}