{"id":"W3123050006","doi":"10.3390/cancers13030410","title":"Specific Inhibition of HIF Activity: Can Peptides Lead the Way?","year":2021,"lang":"en","type":"review","venue":"Cancers","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Lead (geology); Chemistry; Computational biology; Biochemical engineering; Biology; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003705483,0.0007287255,0.00094508,0.0007658461,0.0001533673,0.0007465652,0.0006644137,0.0009444278,0.002520734],"category_scores_gemma":[0.0003825695,0.0002242647,0.0003513909,0.0007730938,0.000398519,0.001350563,0.0004152057,0.002155682,0.002311738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003840417,"about_ca_system_score_gemma":0.0004019697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003944195,"about_ca_topic_score_gemma":0.0006708429,"domain_scores_codex":[0.9999092,0.0000176856,0.000009593538,0.00001693572,0.00003332389,0.00001335201],"domain_scores_gemma":[0.9999088,0.00004129449,0.00001236683,0.000003758728,0.00002104774,0.00001262101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001834321,0.000114082,0.0001274101,0.01081806,0.00007027479,0.0003374258,0.00007124578,0.0004492533,0.01059009,0.008758205,0.03397064,0.9345099],"study_design_scores_gemma":[0.00003269024,0.0001639025,0.0003001653,0.001050981,0.0000441831,0.0009464465,0.00002906954,0.00006950156,0.001796688,0.002067357,0.993485,0.00001410081],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002548982,0.9972824,0.0002809445,0.0004057975,0.0003702391,0.000006277276,0.00002101218,0.00001285009,0.001365621],"genre_scores_gemma":[0.001135936,0.9967565,0.0003015445,0.000385774,0.0001883237,0.00001107058,0.00003724713,0.000003529648,0.001180175],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002520734,"threshold_uncertainty_score":0.008432686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03900702853861635,"score_gpt":0.2980397907480181,"score_spread":0.2590327622094017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}