{"id":"W3123214398","doi":"10.1016/s2213-2600(21)00018-7","title":"α1-Antitrypsin deficiency and the risk of COVID-19: an urgent call to action","year":2021,"lang":"en","type":"article","venue":"The Lancet Respiratory Medicine","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network; Toronto General Hospital","funders":"Canadian Institutes of Health Research; Government of Ontario; Grifols; CSL Behring; Alpha-1 Foundation","keywords":"Coronavirus disease 2019 (COVID-19); Pandemic; Medicine; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Inflammation; Coronavirus; 2019-20 coronavirus outbreak; Intensive care medicine; Immunology; Neutrophil extracellular traps; Virology; Internal medicine; Disease; Outbreak; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01514481,0.001528321,0.008043408,0.002046482,0.001698614,0.006833014,0.004230761,0.03697908,0.01492259],"category_scores_gemma":[0.03780236,0.00127887,0.004507723,0.001305806,0.003792983,0.01257392,0.00373893,0.03432544,0.004844421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002478452,"about_ca_system_score_gemma":0.007073374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005131435,"about_ca_topic_score_gemma":0.006918713,"domain_scores_codex":[0.992644,0.002729755,0.0008465908,0.0008582006,0.002272829,0.0006486421],"domain_scores_gemma":[0.9390306,0.039042,0.004187909,0.001840723,0.008496481,0.007402304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001626009,0.0004754885,0.01157413,0.003554869,0.001429635,0.002125669,0.0006579739,0.0006449491,0.001591857,0.01914988,0.7563934,0.2007762],"study_design_scores_gemma":[0.001294226,0.000857738,0.03078838,0.01366308,0.001918605,0.003567362,0.004089675,0.001886545,0.0002802506,0.1069111,0.8341163,0.0006266231],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001545269,0.2234426,0.001100938,0.7366658,0.03315265,0.00002212156,0.0003559061,0.0001366161,0.003578031],"genre_scores_gemma":[0.02796334,0.2476194,0.00491169,0.3884772,0.3264867,0.0001141252,0.0008232838,0.0001215393,0.003482815],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03697908,"threshold_uncertainty_score":0.0800944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1285395376841502,"score_gpt":0.381362659304177,"score_spread":0.2528231216200268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}