{"id":"W3123244134","doi":"10.1371/journal.ppat.1009275","title":"Ebola virus triggers receptor tyrosine kinase-dependent signaling to promote the delivery of viral particles to entry-conducive intracellular compartments","year":2021,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada; Institute of Infection and Immunity; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science; University of Ottawa; Public Health Agency; Public Health Agency of Canada; Canadian Institutes of Health Research","keywords":"Viral entry; Endosome; Ebola virus; Biology; Receptor tyrosine kinase; Virology; Tyrosine kinase; Viral replication; Host factor; Entry inhibitor; Cell biology; Signal transduction; Virus; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001068046,0.0004576016,0.0003512023,0.0002750016,0.0001562552,0.000291272,0.0001654269,0.0003360416,0.001365657],"category_scores_gemma":[0.00008162691,0.0001448882,0.0003638089,0.000173304,0.0001238781,0.0002673678,0.0002560047,0.0006441735,0.000563536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003619273,"about_ca_system_score_gemma":0.0001708058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004386762,"about_ca_topic_score_gemma":0.0007246935,"domain_scores_codex":[0.9998623,0.00001860657,0.00000848773,0.00002192737,0.00003841945,0.00005026558],"domain_scores_gemma":[0.9999721,0.000006812335,0.000005012869,0.000003404016,0.0000047536,0.000007923584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000954515,0.00004119916,0.0001250593,0.00005875338,0.000007350833,0.00007563801,0.00001163054,0.00005585011,0.9971041,0.0001895501,0.00008345906,0.002151993],"study_design_scores_gemma":[0.00003222651,0.0002840019,0.0043974,0.00001308904,0.00001924135,0.000298577,0.00002704531,0.001218763,0.9868851,0.0001117548,0.006707026,0.000005838008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738411,0.01177196,0.005390256,0.00025641,0.00009354464,0.000108247,0.0008224047,0.0001817962,0.007534358],"genre_scores_gemma":[0.9791116,0.007006626,0.005655285,0.0001953348,0.00003668644,0.0001185903,0.001151871,0.00002043998,0.006703694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001365657,"threshold_uncertainty_score":0.004568577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04262102386750984,"score_gpt":0.2948186735600136,"score_spread":0.2521976496925037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}