{"id":"W3123261984","doi":"10.1016/j.tiv.2021.105097","title":"Transcriptomic pathway and benchmark dose analysis of Bisphenol A, Bisphenol S, Bisphenol F, and 3,3',5,5'-Tetrabromobisphenol A in H9 human embryonic stem cells","year":2021,"lang":"en","type":"article","venue":"Toxicology in Vitro","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Health Canada","funders":"","keywords":"Tetrabromobisphenol A; Bisphenol A; Bisphenol S; Bisphenol; Estrogen receptor; Chemistry; Embryonic stem cell; Estrogen; Transcriptome; Stem cell; Biology; Biochemistry; Cell biology; Gene expression; Gene; Endocrinology; Genetics; Fire retardant; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001224922,0.0003004026,0.0003206114,0.0005469369,0.0003294296,0.0003509085,0.0001507152,0.0003811967,0.001960582],"category_scores_gemma":[0.0001804845,0.0001366198,0.0005772098,0.0007580727,0.0001605908,0.0002214215,0.0002197075,0.0003419807,0.0003115364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003426743,"about_ca_system_score_gemma":0.0004558624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003042796,"about_ca_topic_score_gemma":0.004619952,"domain_scores_codex":[0.9998327,0.0000107669,0.00000994701,0.00007407738,0.00004185791,0.00003069519],"domain_scores_gemma":[0.9998937,0.0000266097,0.00002056929,0.00001017219,0.00003473712,0.00001425395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003152119,0.00003496341,0.004177322,0.00009178423,0.00003924079,0.0000618324,0.000041397,0.000496262,0.9908167,0.000136181,0.0001992348,0.00358984],"study_design_scores_gemma":[0.00003575153,0.0009193835,0.3379832,0.00004257743,0.0003214157,0.0005307857,0.0006041143,0.008716465,0.6404725,0.0008063031,0.009512762,0.00005480946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9599937,0.001041961,0.005085674,0.000157315,0.0000511568,0.00006795794,0.03130168,0.0001595714,0.002140952],"genre_scores_gemma":[0.94606,0.001347178,0.007857164,0.0003429277,0.00001293448,0.0003179379,0.03591827,0.00006950521,0.008074055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003042796,"threshold_uncertainty_score":0.006558776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0094189933264366,"score_gpt":0.2863002804587388,"score_spread":0.2768812871323023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}