{"id":"W3123339396","doi":"10.1016/j.domaniend.2021.106605","title":"Transcriptome and epigenome analysis of porcine embryos from non-esterified fatty acid-exposed oocytes","year":2021,"lang":"en","type":"article","venue":"Domestic Animal Endocrinology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ministère de l'Agriculture, des Pêcheries et de l'Alimentation; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Blastocyst; Transcriptome; Biology; Andrology; Embryo; In vitro maturation; Embryo quality; Embryogenesis; Epigenome; Endocrinology; Internal medicine; Follicular fluid; Fatty acid; DNA methylation; Oocyte; Cell biology; Gene expression; Biochemistry; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001048503,0.0002302869,0.001154262,0.0002503484,0.00005961799,0.000005796175,0.0001003218,0.0001646497,0.00052507],"category_scores_gemma":[0.0003280933,0.0001989864,0.0002110489,0.0005572295,0.0005253071,0.00005224585,0.00007421394,0.000251753,0.00001264605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003177462,"about_ca_system_score_gemma":0.0001125928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001232194,"about_ca_topic_score_gemma":0.00003004106,"domain_scores_codex":[0.9981129,0.0001288231,0.0004985944,0.0007500302,0.0001195356,0.0003900802],"domain_scores_gemma":[0.998787,0.0001906919,0.0001247436,0.0005623638,0.0001966471,0.0001385437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002705829,0.0002099863,0.2761922,0.00003834254,0.001623192,0.000494893,0.0003912116,0.000001660974,0.7175529,0.0002224592,0.0000044552,0.0005629153],"study_design_scores_gemma":[0.001607512,0.0006371742,0.8556769,0.00001116685,0.002023179,0.0001413808,0.0002588531,0.00007129422,0.1391402,0.000158923,0.0001391784,0.0001342929],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932204,0.003852182,0.001100176,0.000789309,0.000134728,0.0002032873,0.0001044668,0.00004471237,0.000550689],"genre_scores_gemma":[0.9980092,0.0002318995,0.001030227,0.0002204504,0.00008531737,0.00001672554,0.0002421493,0.00001382797,0.0001501702],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5794847,"threshold_uncertainty_score":0.8114428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02666843361895972,"score_gpt":0.2906420892873843,"score_spread":0.2639736556684246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}