{"id":"W3123395182","doi":"10.1007/s40291-020-00508-0","title":"Circulating Exosomes of Neuronal Origin as Potential Early Biomarkers for Development of Stroke","year":2021,"lang":"en","type":"review","venue":"Molecular Diagnosis & Therapy","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Microvesicles; Biomarker; Stroke (engine); Medicine; Disease; Bioinformatics; Microvesicle; Exosome; Population; Pathophysiology; Pathology; Neuroscience; microRNA; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003045178,0.0005476262,0.001206064,0.0001624429,0.0000731562,0.00003298016,0.0005907494,0.0004263296,0.00004680629],"category_scores_gemma":[0.0001440238,0.0005506047,0.001380071,0.0002111077,0.0001326419,0.00000497992,0.0001790696,0.0001377629,0.000002702042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003749927,"about_ca_system_score_gemma":0.0009386174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009297675,"about_ca_topic_score_gemma":0.000001290717,"domain_scores_codex":[0.9970734,0.0002929862,0.001029095,0.0007981373,0.0004106143,0.0003957405],"domain_scores_gemma":[0.9980441,0.00008045138,0.0007380553,0.0007655176,0.0002303084,0.0001416085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007466893,0.0004546846,0.00008439305,0.002682402,0.002465725,0.00005848317,0.00004273556,0.00001546418,0.1428564,0.0000751234,0.000138972,0.851051],"study_design_scores_gemma":[0.0008956207,0.0003115446,0.00006456226,0.001908561,0.0005281177,0.00001958884,0.00001757935,0.0000025461,0.2669236,0.00002345508,0.7286788,0.0006260823],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1493883,0.8468681,0.002299775,0.000008045849,0.0001808697,0.001042658,0.0001738271,0.000009901378,0.00002859997],"genre_scores_gemma":[0.0152466,0.9755889,0.006971259,0.0000563776,0.0001227369,0.0007572282,0.00103897,0.0001705446,0.00004735269],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8504249,"threshold_uncertainty_score":0.9996945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03716705244228823,"score_gpt":0.333684149554407,"score_spread":0.2965170971121188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}