{"id":"W3123432876","doi":"10.1186/s13287-021-02136-9","title":"Glucocorticoid agonists enhance retinal stem cell self-renewal and proliferation","year":2021,"lang":"en","type":"article","venue":"Stem Cell Research & Therapy","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Scheme for Promotion of Academic and Research Collaboration; Hospital for Sick Children; Krembil Foundation; Canada First Research Excellence Fund; Ontario Institute for Regenerative Medicine; Foundation Fighting Blindness","keywords":"Stem cell; Glucocorticoid; Cell biology; Biology; Retinal; Neuroscience; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001160488,0.0003155208,0.000248371,0.000279755,0.0001002494,0.000333451,0.0001459753,0.0001983182,0.001687541],"category_scores_gemma":[0.0001493627,0.00006397063,0.0002146553,0.0001416144,0.0001417122,0.0001365024,0.0001651673,0.0003448683,0.0003550519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003168973,"about_ca_system_score_gemma":0.0002163744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006443743,"about_ca_topic_score_gemma":0.001822653,"domain_scores_codex":[0.9998666,0.0000221463,0.00001193917,0.00002034252,0.00005611588,0.00002277327],"domain_scores_gemma":[0.999868,0.00003770805,0.00002849487,0.00001339748,0.00002062287,0.0000317832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001653072,0.00003623737,0.0002628496,0.000103028,0.00000851432,0.00003713229,0.00001248375,0.0001150405,0.9930893,0.0000988282,0.0001070976,0.005964356],"study_design_scores_gemma":[0.00001538761,0.0003613915,0.003312372,0.00001022144,0.00002282542,0.00008258257,0.00002521616,0.0003165511,0.9911583,0.00003819918,0.00465237,0.000004512131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977193,0.01308381,0.003102213,0.0002772215,0.00007719342,0.00007629627,0.0009707965,0.0002534022,0.004965968],"genre_scores_gemma":[0.9897311,0.003862199,0.002768103,0.00008775581,0.00002266358,0.00003633902,0.0005179644,0.00002208064,0.002951604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001687541,"threshold_uncertainty_score":0.005645335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02191158315892083,"score_gpt":0.3051541494491855,"score_spread":0.2832425662902647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}