{"id":"W3123474156","doi":"10.1093/plcell/koaa027","title":"H3.1K27me1 maintains transcriptional silencing and genome stability by preventing GCN5-mediated histone acetylation","year":2020,"lang":"en","type":"article","venue":"The Plant Cell","topic":"Plant Molecular Biology Research","field":"Agricultural and Biological Sciences","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"H2020 European Research Council; Fonds de recherche du Québec – Nature et technologies; National Institutes of Health; National Institute of General Medical Sciences; Wellcome Trust","keywords":"Biology; Histone H3; Heterochromatin protein 1; Heterochromatin; Chromatin; Genetics; Histone; Genome instability; Histone methyltransferase; Arabidopsis; Histone H2A; Histone code; Acetylation; Cell biology; Nucleosome; Mutant; DNA; Gene; DNA damage","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003888125,0.0000963223,0.0001110825,0.00000436726,0.000209406,0.00002511841,0.0001873538,0.00006999849,0.0002582357],"category_scores_gemma":[0.00005057782,0.00003599648,0.00004452641,0.0001161561,0.00008560199,0.00004347682,0.00006107993,0.0001877596,0.00003007472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002310846,"about_ca_system_score_gemma":0.000009585851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009685125,"about_ca_topic_score_gemma":0.00009431345,"domain_scores_codex":[0.9990292,0.0001726833,0.0001444276,0.0002447489,0.0001632416,0.000245761],"domain_scores_gemma":[0.9995239,0.0002722614,0.00004958575,0.00003350675,0.00001920933,0.0001015666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004747377,0.00002277841,0.001372453,0.000009555009,0.000007470399,0.000003267708,0.0003045062,0.000002883512,0.9978217,0.00001361476,0.0001547636,0.0002395476],"study_design_scores_gemma":[0.001727642,0.00156502,0.4230026,0.00005335336,0.0001458836,0.0001331665,0.003814152,0.009746408,0.486512,0.0005683825,0.07129195,0.001439428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941457,0.0005707318,0.00002695521,0.003841455,0.00001832138,0.0002346837,0.0008462801,0.00003954773,0.0002763476],"genre_scores_gemma":[0.9982527,0.00009732098,0.0000220924,0.0003414045,0.00006416845,0.000007096253,0.001134879,8.29476e-7,0.00007948579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5113097,"threshold_uncertainty_score":0.28275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03304022857644071,"score_gpt":0.2086154263929734,"score_spread":0.1755751978165327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}