{"id":"W3123494586","doi":"10.2139/ssrn.3493380","title":"Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development","year":2019,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Retina; Biology; Conserved sequence; Evolutionary biology; Computational biology; Cell biology; Genetics; Neuroscience; Gene; Base sequence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001054856,0.000132795,0.0002329696,0.0003066995,0.0001508357,0.0003208609,0.0001519159,0.0002592826,0.0006683198],"category_scores_gemma":[0.0001951262,0.0001371114,0.000174305,0.0002259045,0.0001875255,0.0001815649,0.0001532385,0.0002165967,0.0003634048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001841219,"about_ca_system_score_gemma":0.00016935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008804016,"about_ca_topic_score_gemma":0.002973511,"domain_scores_codex":[0.9999504,0.000003135542,0.000003153908,0.00002284119,0.00001338749,0.00000712949],"domain_scores_gemma":[0.9998944,0.00003011029,0.00003098083,0.00001521959,0.00001638549,0.00001291015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00003827958,0.000002600753,0.001179333,0.00001876996,0.000005883182,0.00004608346,0.00001877109,0.00007425767,0.9955025,0.00009689996,0.00003143134,0.002985009],"study_design_scores_gemma":[0.00001320636,0.0001362905,0.3121583,0.00001529374,0.0000595436,0.001572712,0.0001172714,0.003923263,0.6774093,0.0007494908,0.003823165,0.00002218037],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860075,0.002685289,0.008399561,0.00007733793,0.00001961133,0.00001257279,0.001038158,0.00009185691,0.001668055],"genre_scores_gemma":[0.9859226,0.001546782,0.008918079,0.00008029623,0.00001086543,0.00002510705,0.001412089,0.00005652116,0.002027797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008804016,"threshold_uncertainty_score":0.00223577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0119452871367197,"score_gpt":0.2061273447138122,"score_spread":0.1941820575770925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}