{"id":"W3123498216","doi":"10.1158/1940-6207.capr-20-0470","title":"Diet-Dependent Metabolic Regulation of DNA Double-Strand Break Repair in Cancer: More Choices on the Menu","year":2021,"lang":"en","type":"review","venue":"Cancer Prevention Research","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Epigenetics; DNA methylation; Biology; DNA damage; DNA repair; Cancer; Carcinogenesis; Genome instability; Histone; DNA; Methionine; Cancer research; Cell biology; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006761889,0.000783612,0.001575257,0.001585117,0.0003147217,0.001402016,0.0009272356,0.001359308,0.00419862],"category_scores_gemma":[0.0008322853,0.000265314,0.0005241912,0.002006704,0.0006352863,0.002435033,0.0007878157,0.002670941,0.001990863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007654651,"about_ca_system_score_gemma":0.001100628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009428221,"about_ca_topic_score_gemma":0.00179503,"domain_scores_codex":[0.9998135,0.00004409051,0.00002666706,0.00003568362,0.00005834279,0.00002169309],"domain_scores_gemma":[0.9996098,0.0002088291,0.00004057384,0.00001473257,0.00009141947,0.00003484064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001350589,0.00007092412,0.0001626496,0.02100005,0.0001349887,0.0002533564,0.0001117314,0.0003300347,0.002536794,0.008160518,0.05777026,0.9093336],"study_design_scores_gemma":[0.0000129109,0.00008650697,0.000512262,0.003993324,0.00006290041,0.0006466113,0.00006848331,0.00004433311,0.0002634436,0.003472461,0.9908187,0.0000180758],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005994196,0.9979383,0.00009649296,0.0006914731,0.0004824839,0.00000194482,0.00001160028,0.000006753929,0.0007110655],"genre_scores_gemma":[0.0003753898,0.998138,0.0001208507,0.0004312971,0.0003028776,0.000003459538,0.00002027273,0.000002204803,0.0006056908],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00419862,"threshold_uncertainty_score":0.01404577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1588753686475106,"score_gpt":0.4731740759979638,"score_spread":0.3142987073504533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}