{"id":"W3123557566","doi":"10.1128/aac.02353-20","title":"Variability of Hydroxy-Itraconazole in Relation to Itraconazole Bloodstream Concentrations","year":2021,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Itraconazole; Medicine; Microbiology; Biology; Antifungal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002592366,0.0002063078,0.0004518871,0.0005541323,0.0001832946,0.001027705,0.0003191613,0.0004274658,0.001052533],"category_scores_gemma":[0.009730157,0.0001451031,0.000273239,0.000870272,0.0003302497,0.00038931,0.0005106021,0.0006123229,0.0003867774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002172532,"about_ca_system_score_gemma":0.0001288909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009073928,"about_ca_topic_score_gemma":0.0005566679,"domain_scores_codex":[0.9966619,0.00105256,0.0003760784,0.0009162438,0.0007823085,0.0002110116],"domain_scores_gemma":[0.9882895,0.006362497,0.002367212,0.0017854,0.0008805364,0.0003149085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001539911,0.00009103858,0.9495903,0.00005118826,0.0005456674,0.0002917102,0.0005403954,0.001948227,0.011206,0.0003115555,0.0005701095,0.03331392],"study_design_scores_gemma":[0.000007992553,0.0002172161,0.9905439,0.00001040292,0.00004864793,0.0006902061,0.0001057062,0.004265845,0.002881215,0.0003689942,0.0008430533,0.00001674306],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915799,0.0009881238,0.004118549,0.00005892607,0.00003377466,0.00002731201,0.0008483999,0.00007179941,0.00227318],"genre_scores_gemma":[0.9991715,0.00005525815,0.000273946,0.00001357239,0.00001140132,0.000007254177,0.0003179305,0.000008513536,0.0001406506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002592366,"threshold_uncertainty_score":0.0137099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01151039839488906,"score_gpt":0.2745017327794625,"score_spread":0.2629913343845734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}