{"id":"W3123698564","doi":"10.2139/ssrn.3732360","title":"Two-Component Spike Nanoparticle Vaccine Protects Macaques from SARS-CoV-2 Infection","year":2020,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Virology; Pandemic; Immunity; Coronavirus disease 2019 (COVID-19); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Immunization; Medicine; Biology; Immune system; Immunology; Infectious disease (medical specialty); Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001769347,0.0003810953,0.0003522265,0.0001865498,0.0001355995,0.0003147778,0.0002285603,0.000667645,0.001070864],"category_scores_gemma":[0.0002023657,0.0001057547,0.0002185511,0.00005250322,0.000177858,0.0002454837,0.0001729372,0.0005479353,0.0003094805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002309619,"about_ca_system_score_gemma":0.0002777456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006921211,"about_ca_topic_score_gemma":0.0008500111,"domain_scores_codex":[0.9999031,0.00001373041,0.000005625046,0.00001877254,0.00002064739,0.00003815017],"domain_scores_gemma":[0.9999304,0.00001118726,0.00001354211,0.000009640692,0.00001384831,0.00002142825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001250827,0.0008474915,0.0007681325,0.00006535436,0.00003353446,0.00007444623,0.00004696214,0.0003105908,0.984945,0.0001795312,0.0004285694,0.01104954],"study_design_scores_gemma":[0.0008618284,0.033966,0.02647274,0.00007125942,0.000256892,0.001018297,0.0003301531,0.008596319,0.9159409,0.0006810359,0.01176948,0.00003507771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981159,0.0003596876,0.0006395532,0.0001101371,0.00008589251,0.00002908752,0.00007878302,0.00004489953,0.0005360996],"genre_scores_gemma":[0.9963787,0.0002341817,0.0007684609,0.0001547739,0.00002727586,0.00002940442,0.0002893659,0.000009512031,0.002108282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001070864,"threshold_uncertainty_score":0.003582358,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03168927846222754,"score_gpt":0.3278665649883118,"score_spread":0.2961772865260843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}