{"id":"W3123950703","doi":"10.7554/elife.62858","title":"The rise and fall of the ancient northern pike master sex-determining gene","year":2021,"lang":"en","type":"article","venue":"eLife","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; University of Victoria","funders":"National Institute of Environmental Health Sciences; National Institute of General Medical Sciences; Korea National Institute of Health; National Institutes of Health; Agence Nationale de la Recherche; Deutsche Forschungsgemeinschaft","keywords":"Pike; Biology; Evolutionary biology; Population; Gene duplication; Evolution of sexual reproduction; Esox; Gene; Genetics; Demography; Fish <Actinopterygii>","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001159352,0.00007258659,0.00007695803,0.000003861165,0.0001301647,0.00002436561,0.0001331486,0.00005049944,0.000009690382],"category_scores_gemma":[0.00007075892,0.00004222921,0.00006481317,0.00003059268,0.0001496028,0.000001476128,0.0001872456,0.00004939904,0.000002832774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002338342,"about_ca_system_score_gemma":0.00005179515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000371661,"about_ca_topic_score_gemma":0.0001349088,"domain_scores_codex":[0.999364,0.00005017129,0.0001790676,0.0001520743,0.0001332987,0.0001213425],"domain_scores_gemma":[0.9995206,0.00002205154,0.00006667698,0.0002507311,0.00009726849,0.0000426812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009138987,0.0002399157,0.4176243,0.00007752781,0.0001894171,0.00002408831,0.001212068,0.00008471646,0.468869,0.0002952156,0.002252833,0.1090395],"study_design_scores_gemma":[0.000569375,0.0001820438,0.1017914,0.00002009811,0.00002548002,0.00005212595,0.001519416,0.0001370629,0.7085388,0.00007675212,0.1869111,0.000176424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957092,0.002365445,0.00004797001,0.0004646391,0.0001299809,0.00004637279,0.000008733156,0.000002705441,0.001224978],"genre_scores_gemma":[0.9925561,0.0003934368,0.0001127699,0.0005579732,0.0001102069,0.000004984428,0.000003150839,0.000006524987,0.006254867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3158329,"threshold_uncertainty_score":0.1722057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01218928466078859,"score_gpt":0.2346732166561985,"score_spread":0.2224839319954099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}