{"id":"W3124305292","doi":"10.3390/cells10020198","title":"Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation","year":2021,"lang":"en","type":"article","venue":"Cells","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; National Institute of Diabetes and Digestive and Kidney Diseases; Institute of Aging; National Cancer Institute; National Institute on Aging","keywords":"Microglia; ABCA1; Lipoprotein lipase; Cholesterol; Efflux; Chemistry; Lipid droplet; Endocrinology; Internal medicine; Biology; Inflammation; Biochemistry; Cell biology; Medicine; Adipose tissue; Gene; Transporter","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002251262,0.0003382546,0.0003422019,0.0004559548,0.0003071041,0.000646466,0.0001700225,0.0004842699,0.001357023],"category_scores_gemma":[0.0002075569,0.0002061565,0.0003504887,0.0002052988,0.0004106459,0.0002872178,0.0003995582,0.0006222288,0.0009880691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005267659,"about_ca_system_score_gemma":0.0003365785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007524703,"about_ca_topic_score_gemma":0.0009970735,"domain_scores_codex":[0.9998276,0.00003628491,0.00001646514,0.00002862412,0.00002817309,0.0000629129],"domain_scores_gemma":[0.9998448,0.00001354074,0.00005104165,0.00001271053,0.00003232314,0.00004562742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006519448,0.00005802383,0.0007040873,0.00006619583,0.000009714658,0.0001694479,0.00003412933,0.00006702207,0.9960133,0.0002037945,0.0001672369,0.001855118],"study_design_scores_gemma":[0.0001975654,0.0005372613,0.03928416,0.00006727775,0.00007105053,0.0009715879,0.000478028,0.002582871,0.9482892,0.001612803,0.005871536,0.00003656559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856946,0.007284507,0.002892254,0.0009256881,0.000101104,0.00003623028,0.0003970877,0.0001610077,0.002507682],"genre_scores_gemma":[0.9927925,0.002849938,0.0009891759,0.000142802,0.00003041111,0.00004271983,0.0002110931,0.00002876582,0.002912536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001357023,"threshold_uncertainty_score":0.004539669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.013128664592254,"score_gpt":0.2527690565329307,"score_spread":0.2396403919406767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}