{"id":"W3124546863","doi":"10.1200/jco.20.03256","title":"Initial Management of Noncastrate Advanced, Recurrent, or Metastatic Prostate Cancer: ASCO Guideline Update","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Health Sciences Centre; Ottawa Hospital; University of British Columbia","funders":"","keywords":"Medicine; Enzalutamide; Docetaxel; Prostate cancer; Abiraterone acetate; Guideline; Oncology; Androgen deprivation therapy; Internal medicine; Cancer; Clinical trial; Radiation therapy; Management of prostate cancer; Gynecology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009712401,0.001245751,0.002332463,0.004771865,0.0006882945,0.00250277,0.003396253,0.003688401,0.004777444],"category_scores_gemma":[0.02961591,0.000655802,0.004162675,0.004679936,0.0006981409,0.002128252,0.001817324,0.003971268,0.002964183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003781723,"about_ca_system_score_gemma":0.01788479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02455055,"about_ca_topic_score_gemma":0.05295906,"domain_scores_codex":[0.9920279,0.002818661,0.002228082,0.0003523429,0.002182591,0.0003903586],"domain_scores_gemma":[0.9770447,0.004649163,0.003551075,0.0004800974,0.01315407,0.001120933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001164127,0.0001041195,0.002010717,0.03242002,0.0006502913,0.0001856687,0.0002535723,0.0005623143,0.0004054434,0.001661904,0.6505116,0.3111179],"study_design_scores_gemma":[0.0003994782,0.0001737455,0.005075384,0.1154031,0.002192092,0.0007388155,0.0002285873,0.0004343885,0.0003116716,0.00285355,0.8721002,0.00008904386],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.003282242,0.7969868,0.006095669,0.1350937,0.01266712,0.002735123,0.01068354,0.0005774569,0.03187839],"genre_scores_gemma":[0.01652411,0.8188965,0.04674382,0.07432289,0.007265669,0.003378498,0.02133417,0.0002531075,0.01128124],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.02455055,"threshold_uncertainty_score":0.05136466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2214922719406866,"score_gpt":0.5749504827356309,"score_spread":0.3534582107949442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}