{"id":"W3124761826","doi":"10.1111/jcmm.16222","title":"The pioneer and differentiation factor FOXA2 is a key driver of yolk‐sac tumour formation and a new biomarker for paediatric and adult yolk‐sac tumours","year":2021,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Testicular diseases and treatments","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Heinrich-Heine-Universität Düsseldorf; Stem Cell Network; Wilhelm Sander-Stiftung","keywords":"Yolk sac; Biology; Epigenetics; FOXA2; Wnt signaling pathway; DNA methylation; Cancer research; microRNA; GATA3; Cell biology; Genetics; Gene expression; Gene; Transcription factor; Embryo","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000565983,0.000388629,0.0003762559,0.0007815742,0.000193876,0.0005558801,0.0002035913,0.0003602303,0.00110704],"category_scores_gemma":[0.0005794526,0.0002188338,0.0002819706,0.000613922,0.0002695748,0.0003922889,0.0003073429,0.0004308361,0.0002428072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003736437,"about_ca_system_score_gemma":0.0003094725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001792536,"about_ca_topic_score_gemma":0.002533883,"domain_scores_codex":[0.9997588,0.00002580426,0.00001450146,0.00009000208,0.00008051033,0.0000302747],"domain_scores_gemma":[0.9997095,0.00007233232,0.00009928494,0.00002061123,0.00006116745,0.00003701949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007424203,0.0000436631,0.2328384,0.0009544559,0.0003255988,0.0006049853,0.0002115363,0.0010455,0.7198809,0.0009664429,0.001704468,0.04068163],"study_design_scores_gemma":[0.00004210868,0.0004207699,0.6346082,0.0001405456,0.0006666959,0.004083201,0.0002846803,0.007095639,0.3107578,0.001361174,0.04048416,0.00005507459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9296998,0.03958903,0.02112074,0.0004128857,0.00009679007,0.00005884521,0.004654014,0.0002967736,0.004071118],"genre_scores_gemma":[0.978967,0.006534246,0.008572798,0.0001870713,0.0000561752,0.00005864652,0.003274066,0.00005397846,0.002296107],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001792536,"threshold_uncertainty_score":0.003703415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01209161435107367,"score_gpt":0.2462795567362148,"score_spread":0.2341879423851412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}