{"id":"W3124975684","doi":"10.1002/bies.202000156","title":"Cancer and the breakdown of multicellularity: What <i>Dictyostelium discoideum</i>, a social amoeba, can teach us","year":2021,"lang":"en","type":"review","venue":"BioEssays","topic":"Protist diversity and phylogeny","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trent University; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Dictyostelium discoideum; Multicellular organism; Biology; Amoeba (genus); Dictyostelium; Carcinogenesis; Gene; Cell biology; Evolutionary biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004006078,0.0005948764,0.0006966239,0.001758163,0.0002978301,0.001007976,0.0006817442,0.001353919,0.001600125],"category_scores_gemma":[0.0007068126,0.0002466473,0.0003445783,0.001585514,0.0008625704,0.002257767,0.000605597,0.00181515,0.00138831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008958947,"about_ca_system_score_gemma":0.0009791879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001864872,"about_ca_topic_score_gemma":0.002777797,"domain_scores_codex":[0.9998677,0.00002780774,0.00001584487,0.0000292724,0.00004097597,0.000018399],"domain_scores_gemma":[0.9997525,0.0001059178,0.00003123123,0.00001156476,0.0000613024,0.00003761405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007821395,0.00003354839,0.0002410016,0.01201569,0.00007002648,0.0001930072,0.0001190791,0.0003551572,0.002130579,0.01178877,0.05823995,0.914735],"study_design_scores_gemma":[0.000006900779,0.00004981162,0.0006570552,0.001917986,0.0000286891,0.000733788,0.00005288517,0.00005138649,0.000273113,0.00323386,0.9929816,0.00001290025],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007517175,0.9980052,0.00007378504,0.0007639265,0.0002891869,0.000001229426,0.00000975988,0.00000452233,0.0007773064],"genre_scores_gemma":[0.0006954023,0.9976509,0.00009965344,0.0005544857,0.0003730783,0.000002983529,0.00001807542,0.000001457222,0.0006039155],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001864872,"threshold_uncertainty_score":0.006500125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02509719596262442,"score_gpt":0.2933312211856254,"score_spread":0.268234025223001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}