{"id":"W3125119901","doi":"10.1080/17474086.2021.1875817","title":"Key questions in the new hemophilia era: update on concomitant use of FVIII and emicizumab in hemophilia A patients with inhibitors","year":2021,"lang":"en","type":"review","venue":"Expert Review of Hematology","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Clinical Evaluative Sciences; SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Medicine; Bispecific antibody; Concomitant; Expert opinion; Immunology; Monoclonal antibody; Intensive care medicine; Antibody; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001030004,0.0007103508,0.001845174,0.00204562,0.0002348085,0.001107492,0.0009749087,0.00155559,0.006708431],"category_scores_gemma":[0.002417771,0.0002521898,0.001160017,0.002072649,0.0003545615,0.001577731,0.0005728694,0.001956911,0.001448359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007052775,"about_ca_system_score_gemma":0.001405686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001495245,"about_ca_topic_score_gemma":0.002815579,"domain_scores_codex":[0.9995561,0.0001209136,0.00009018867,0.00006243207,0.0001427853,0.00002756226],"domain_scores_gemma":[0.9987366,0.0007162485,0.0002138501,0.00001708545,0.0002675634,0.00004874788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001111884,0.00004151898,0.000173502,0.06163116,0.000253011,0.0001716477,0.00008106137,0.0001957097,0.0004143777,0.001915541,0.07960606,0.8554052],"study_design_scores_gemma":[0.00005635306,0.0001005275,0.0009589013,0.04310411,0.0007039189,0.001488576,0.00009304055,0.000087921,0.0001208597,0.001491898,0.9517723,0.00002163071],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003480928,0.998834,0.00003149373,0.0005426879,0.0002441519,0.000002999247,0.0000160942,0.000003068944,0.0002908653],"genre_scores_gemma":[0.000321846,0.9985865,0.00007758744,0.0004895451,0.0002977091,0.000004714525,0.00002954807,0.000001182703,0.0001913982],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006708431,"threshold_uncertainty_score":0.02244198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03813247909115668,"score_gpt":0.3637584852496163,"score_spread":0.3256260061584597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}