{"id":"W3125141442","doi":"10.1186/s12964-020-00693-9","title":"Phosphatases in toll-like receptors signaling: the unfairly-forgotten","year":2021,"lang":"en","type":"review","venue":"Cell Communication and Signaling","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Signal transduction; Receptor; TRIF; Phosphatase; Kinase; Biology; Phosphorylation; Ubiquitin; Immunology; Innate immune system; Toll-like receptor; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000564802,0.0008341956,0.0008060905,0.001247039,0.0003552701,0.001238567,0.0008099349,0.001496537,0.005301339],"category_scores_gemma":[0.0006467263,0.0002644796,0.0003965139,0.001525459,0.0007432002,0.002516686,0.0008069786,0.003398661,0.004815777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007798973,"about_ca_system_score_gemma":0.0009030841,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007530155,"about_ca_topic_score_gemma":0.001471312,"domain_scores_codex":[0.999815,0.0000335593,0.00001866514,0.00003288297,0.00007167897,0.00002814041],"domain_scores_gemma":[0.9997172,0.00009843868,0.00002860045,0.00001069971,0.00009458551,0.00005042834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001342127,0.00005113383,0.0001425139,0.00722986,0.00005268841,0.0002486192,0.00005884823,0.0003069821,0.002553617,0.01113259,0.1290021,0.8490868],"study_design_scores_gemma":[0.00001073301,0.0000471927,0.0001760845,0.0007171902,0.00002418044,0.0005758046,0.00003296332,0.00008144205,0.0004734801,0.003046437,0.9948047,0.000009735385],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001049744,0.9959019,0.0001965077,0.001432233,0.0009829493,0.000002566617,0.00002282142,0.00001341093,0.001342613],"genre_scores_gemma":[0.0009848344,0.9950347,0.000216572,0.0008328204,0.001026285,0.000004141298,0.00004447846,0.000003988124,0.001852109],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005301339,"threshold_uncertainty_score":0.01773471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03093598339849696,"score_gpt":0.2990421907057281,"score_spread":0.2681062073072312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}