{"id":"W3125242144","doi":"10.1002/onco.13692","title":"Selinexor, a First in Class, Nuclear Export Inhibitor for the Treatment of Advanced Malignant Peripheral Nerve Sheath Tumor","year":2021,"lang":"en","type":"article","venue":"The Oncologist","topic":"Neurofibromatosis and Schwannoma Cases","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute","keywords":"Medicine; Malignant peripheral nerve sheath tumor; Peripheral; Peripheral nerve; Nuclear export signal; Cancer research; Surgery; Pathology; Internal medicine; Anatomy; Cell nucleus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000116832,0.0003612684,0.0002943467,0.0003957932,0.0005026808,0.0002192469,0.0002411098,0.0004648283,0.0008346523],"category_scores_gemma":[0.0003848745,0.0001260235,0.0004214887,0.0001561152,0.0004548162,0.0002261362,0.0002719525,0.0006017637,0.0002937823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003129686,"about_ca_system_score_gemma":0.0001995938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003969773,"about_ca_topic_score_gemma":0.001317159,"domain_scores_codex":[0.999908,0.00001149783,0.00001669621,0.00001769676,0.000021054,0.00002501517],"domain_scores_gemma":[0.9998221,0.00005970095,0.0000426617,0.00001532055,0.0000104196,0.00004988991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.001438436,0.0010263,0.06531297,0.0005778115,0.0002786139,0.597781,0.001182853,0.002347672,0.1103916,0.001043733,0.002935542,0.2156835],"study_design_scores_gemma":[0.0002902491,0.004390997,0.04619776,0.0000434506,0.0001965895,0.8747616,0.0002385808,0.001494477,0.04810024,0.0003990274,0.02384684,0.00004021238],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778437,0.009098642,0.004344401,0.0009226407,0.0001010455,0.0001341237,0.0001304918,0.0001314535,0.007293471],"genre_scores_gemma":[0.9931179,0.003135269,0.001292509,0.0002436449,0.00005981198,0.00002479257,0.0001041779,0.00001533691,0.002006629],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008346523,"threshold_uncertainty_score":0.00279218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03363152014919998,"score_gpt":0.2939988963940334,"score_spread":0.2603673762448334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}