{"id":"W3125464124","doi":"10.20944/preprints201909.0329.v1","title":"The Uterine-Chemokine-Brain Axis: Menstrual Cycle-Associated Symptoms (MCAS) are in Part Mediated by CCL2, CCL5, CCL11, CXCL8 and CXCL10","year":2019,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Faculty of Medicine, Chulalongkorn University; Chulalongkorn University","keywords":"CCL5; Menstrual cycle; Chemokine; Medicine; CCL11; CCL2; Internal medicine; Endocrinology; Immunology; Hormone; Inflammation; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001961952,0.0002136479,0.0001571067,0.0002994316,0.0001513783,0.0002297732,0.0001066975,0.0001374342,0.001563984],"category_scores_gemma":[0.0008586339,0.0001136858,0.0001310394,0.0002956548,0.00014634,0.0001200902,0.0001694011,0.0001551821,0.0001357909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001765982,"about_ca_system_score_gemma":0.000237513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001843043,"about_ca_topic_score_gemma":0.003548263,"domain_scores_codex":[0.9998944,0.00004430108,0.000005582964,0.00001396317,0.00001720701,0.00002454209],"domain_scores_gemma":[0.9997202,0.00005324065,0.0001615319,0.000009536624,0.00002256397,0.00003308512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00100084,0.0001196268,0.9641886,0.0001160011,0.0001329241,0.0002762995,0.0001491851,0.0001143097,0.01160526,0.00008809396,0.0004744221,0.02173434],"study_design_scores_gemma":[0.00000851531,0.000139656,0.9987727,0.00001037408,0.00001592056,0.0002278125,0.00004160665,0.0001601447,0.0002981417,0.00001766432,0.0003057742,0.000001849742],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970393,0.001922454,0.0001306228,0.00009145471,0.00000748126,0.00002223401,0.0002523935,0.00000687829,0.0005271038],"genre_scores_gemma":[0.9986058,0.0005914737,0.0001774728,0.00003366107,0.00001120227,0.0000227846,0.0002142367,0.000001351741,0.0003421071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001843043,"threshold_uncertainty_score":0.005232096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03649316885974772,"score_gpt":0.2935915448935705,"score_spread":0.2570983760338228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}