{"id":"W3125585717","doi":"10.1021/jacs.0c10810","title":"Detection of SARS-CoV-2 Viral Particles Using Direct, Reagent-Free Electrochemical Sensing","year":2021,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"SARS-CoV-2 detection and testing","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; Sunnybrook Health Science Centre; University of Toronto","funders":"University of Toronto","keywords":"Chemistry; Reagent; Analyte; Amperometry; Aptamer; Nucleic acid; Electrode; Linker; Virus; Virology; Chromatography; Nanotechnology; Electrochemistry; Biochemistry; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000279851,0.0001433595,0.0004989723,0.00002396827,0.00008248525,0.00001784841,0.0001485429,0.00007062573,0.000001904593],"category_scores_gemma":[0.001446394,0.0001069739,0.0007355402,0.0006248644,0.0003144013,0.00006430619,0.0001242319,0.0005630333,5.907198e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002776689,"about_ca_system_score_gemma":0.0001680947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005199956,"about_ca_topic_score_gemma":0.000002011078,"domain_scores_codex":[0.998502,0.00008417363,0.0005409576,0.0001683065,0.0004382974,0.0002663241],"domain_scores_gemma":[0.9983186,0.0001810116,0.0007786089,0.0003110212,0.0003555021,0.0000553086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001389529,0.00009093787,0.0007901055,0.00002464341,0.0001809,0.00001341639,0.000143165,0.000001401593,0.9949639,7.028153e-7,0.0002119841,0.003439914],"study_design_scores_gemma":[0.0007633084,0.00009748468,0.0002728958,0.0001257186,0.0002710183,0.00164301,0.0002985083,0.002911222,0.9931126,0.0001426478,0.0002587244,0.0001029167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975614,0.0001774149,0.001455636,0.000500806,0.0001267112,0.00005154542,0.000001067399,0.0000254307,0.00009996847],"genre_scores_gemma":[0.9825941,0.00001549731,0.01513263,0.001861552,0.0003680448,2.780066e-7,2.447102e-7,0.00002328371,0.000004371174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01496732,"threshold_uncertainty_score":0.4362268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03613971324121121,"score_gpt":0.3059470691056771,"score_spread":0.2698073558644659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}