{"id":"W3125585717","doi":"10.1021/jacs.0c10810","title":"Detection of SARS-CoV-2 Viral Particles Using Direct, Reagent-Free Electrochemical Sensing","year":2021,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"SARS-CoV-2 detection and testing","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; Sunnybrook Health Science Centre; University of Toronto","funders":"University of Toronto","keywords":"Chemistry; Reagent; Analyte; Amperometry; Aptamer; Nucleic acid; Electrode; Linker; Virus; Virology; Chromatography; Nanotechnology; Electrochemistry; Biochemistry; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006444695,0.0006415824,0.0003037401,0.0003385321,0.0001509683,0.0005928792,0.000576328,0.0008181063,0.0007797159],"category_scores_gemma":[0.0006893763,0.0003439688,0.0002349552,0.0001905917,0.0003330186,0.0005070434,0.0005296993,0.0005712525,0.0005957374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002740768,"about_ca_system_score_gemma":0.0002504796,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003162659,"about_ca_topic_score_gemma":0.00100939,"domain_scores_codex":[0.9990552,0.0001592058,0.0000447178,0.0001943604,0.0004959945,0.00005057636],"domain_scores_gemma":[0.9998162,0.00006545589,0.00003517955,0.0000181494,0.00005187823,0.00001317749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002419159,0.00002578981,0.0002545565,0.00009038424,0.000007845514,0.00003361586,0.00002510445,0.00007235168,0.992942,0.0001533326,0.0001685029,0.006202472],"study_design_scores_gemma":[0.00000540632,0.0001549506,0.0007964663,0.000006678417,0.000008017579,0.0002178065,0.00002131703,0.001361912,0.9946208,0.00004448218,0.002752026,0.00001000007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7526368,0.01566293,0.2132862,0.001034143,0.0005043881,0.0004788742,0.0009273498,0.001371337,0.01409796],"genre_scores_gemma":[0.8428259,0.006181082,0.1371557,0.000772951,0.0001339008,0.0002101073,0.0006016942,0.00004390184,0.01207476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008181063,"threshold_uncertainty_score":0.003408372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03613971324121121,"score_gpt":0.3059470691056771,"score_spread":0.2698073558644659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}