{"id":"W3125604524","doi":"10.1242/dmm.046235","title":"Mutant Cx30-A88V mice exhibit hydrocephaly and sex-dependent behavioral abnormalities, implicating a functional role for Cx30 in the brain","year":2021,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Canada First Research Excellence Fund","keywords":"Mutant; Biology; Neuroscience; Sexual differentiation; Psychology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003150548,0.0001946728,0.0001614318,0.00003283682,0.0001495688,0.00004967849,0.0001572835,0.0001237548,0.00002639225],"category_scores_gemma":[0.0000299837,0.0001673306,0.0001175226,0.00005460812,0.00003826975,0.00001008703,0.0001476392,0.00009890839,0.000001121081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001860793,"about_ca_system_score_gemma":0.0001664296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007196848,"about_ca_topic_score_gemma":0.0002189549,"domain_scores_codex":[0.9986153,0.0001103377,0.0002372151,0.000553243,0.0001405752,0.0003433719],"domain_scores_gemma":[0.999359,0.00003943855,0.00006318747,0.0003403266,0.00007175814,0.0001263189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002503926,0.000285039,0.0001816099,0.00003633292,0.00003847937,0.00004122094,0.000515271,0.0003417445,0.9736698,0.02055837,0.00009376279,0.003987978],"study_design_scores_gemma":[0.009758601,0.00176028,0.002730568,0.0001107261,0.0005770748,0.0007444257,0.01524223,0.08098468,0.6071868,0.2585486,0.0197082,0.002647818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9570513,0.001607921,0.03956447,0.0007652229,0.00006549809,0.0003723055,0.0004521113,0.00001398454,0.0001071336],"genre_scores_gemma":[0.9958271,0.00004853957,0.0005116734,0.002064521,0.0001346385,0.0003029801,0.0007576716,0.00002464022,0.0003281865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.366483,"threshold_uncertainty_score":0.6823542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02063914654237395,"score_gpt":0.2556868348974239,"score_spread":0.2350476883550499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}