{"id":"W3125927629","doi":"10.1186/s12916-020-01895-1","title":"Plasma sex hormones and risk of conventional and serrated precursors of colorectal cancer in postmenopausal women","year":2021,"lang":"en","type":"article","venue":"BMC Medicine","topic":"Colorectal Cancer Screening and Detection","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Key Research and Development Program of China; Entertainment Industry Foundation; National Cancer Institute; National Institutes of Health; Gary Bennett Family Fund; Natural Science Foundation of Jiangsu Province; Government of Jiangsu Province; National Heart, Lung, and Blood Institute; American Institute for Cancer Research; National Natural Science Foundation of China; American Cancer Society","keywords":"Medicine; Sex hormone-binding globulin; Testosterone (patch); Odds ratio; Internal medicine; Estrone; Quartile; Colorectal cancer; Adenoma; Hormone; Endocrinology; Confidence interval; Colorectal adenoma; Cancer; Gastroenterology; Androgen","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004120957,0.0001879155,0.0002111982,0.000521819,0.0001485678,0.0002941478,0.000193424,0.0002251912,0.0007671673],"category_scores_gemma":[0.001444446,0.0001789797,0.0002267526,0.0005424752,0.0001862515,0.0001568193,0.0001921943,0.0002905659,0.00009917779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001351633,"about_ca_system_score_gemma":0.0001384091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002449204,"about_ca_topic_score_gemma":0.002830455,"domain_scores_codex":[0.9998335,0.00003690478,0.0000187175,0.00004181191,0.00004476732,0.00002423368],"domain_scores_gemma":[0.9991042,0.0001624257,0.0004981434,0.00004858538,0.00008023464,0.000106358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009800307,0.000003675159,0.9992087,0.000006390846,0.00002347191,0.0000361371,0.00001732436,0.000007076505,0.0001355203,0.000002884052,0.00001270984,0.0004480656],"study_design_scores_gemma":[0.000004396278,0.00006243899,0.9994057,0.000003660303,0.00002204605,0.0003085401,0.00003042566,0.00004139303,0.00003840948,0.000007924817,0.00007409887,0.000001034088],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982113,0.001342357,0.00004952368,0.00001914433,0.000003316029,0.000003043676,0.0001776616,0.000002445562,0.0001912739],"genre_scores_gemma":[0.9995759,0.000226479,0.0000474556,0.000006509846,0.000005548236,0.000002229388,0.00009007553,5.12104e-7,0.00004526889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002449204,"threshold_uncertainty_score":0.004869938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01439268366895132,"score_gpt":0.2735359902566493,"score_spread":0.259143306587698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}