{"id":"W3125993797","doi":"10.1101/2021.01.22.427482","title":"Developmental and behavioral phenotypes in a new mouse model of DDX3X syndrome","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"Neuroscience; Haploinsufficiency; Glutamatergic; Prefrontal cortex; Synaptogenesis; Psychology; Biology; Phenotype; Cognition; Genetics; Glutamate receptor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005262759,0.001187235,0.0004349296,0.002288409,0.0004591643,0.0005787933,0.0006812204,0.001192134,0.003889007],"category_scores_gemma":[0.0002151362,0.0003859026,0.0005024881,0.0004089029,0.000747078,0.0004126164,0.0006844391,0.001315244,0.001122734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005160949,"about_ca_system_score_gemma":0.0003675349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007578716,"about_ca_topic_score_gemma":0.001502171,"domain_scores_codex":[0.9995765,0.00005082882,0.00006434477,0.0000951326,0.0001722161,0.00004105819],"domain_scores_gemma":[0.9996896,0.00005834708,0.00007185764,0.00004055124,0.00003690187,0.0001027347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001889784,0.0001326652,0.0004557439,0.00006390068,0.00001852557,0.0006858181,0.00007363675,0.0002299965,0.9923114,0.00209296,0.0006047414,0.003141575],"study_design_scores_gemma":[0.0002279777,0.0006948942,0.009439072,0.00009669065,0.0001116006,0.006432546,0.0001387658,0.004749761,0.9481942,0.001807538,0.02806057,0.00004636787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9274428,0.002559507,0.04768603,0.001833786,0.0003891263,0.0002577893,0.008477496,0.002279094,0.009074267],"genre_scores_gemma":[0.8509422,0.003336826,0.07378094,0.0009543364,0.0001123558,0.001077925,0.009460689,0.001515818,0.05881877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003889007,"threshold_uncertainty_score":0.01300997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01679555194905291,"score_gpt":0.2197898274739375,"score_spread":0.2029942755248846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}