{"id":"W3126003668","doi":"10.1200/jco.2021.39.3_suppl.tps351","title":"Phase III study of NUC-1031 + cisplatin vs gemcitabine + cisplatin for first-line treatment of patients with advanced biliary tract cancer (NuTide:121).","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cholangiocarcinoma and Gallbladder Cancer Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"NuCana","keywords":"Gemcitabine; Cisplatin; Medicine; Tolerability; Internal medicine; Oncology; Gallbladder cancer; Chemotherapy; Cancer; Biliary tract cancer; Phases of clinical research; Biliary tract; Gastroenterology; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002028429,0.001528576,0.002318166,0.0004829328,0.0003899615,0.0009681775,0.001125942,0.001459674,0.006476722],"category_scores_gemma":[0.001181099,0.0006811221,0.001313933,0.0004628091,0.0008997284,0.0009213849,0.0004666125,0.002798842,0.00116304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001174909,"about_ca_system_score_gemma":0.002030587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001309831,"about_ca_topic_score_gemma":0.003485426,"domain_scores_codex":[0.9995325,0.0002795284,0.0000212577,0.00006158809,0.00004123472,0.0000639974],"domain_scores_gemma":[0.9991647,0.0001360369,0.0001390661,0.00007988514,0.00005885123,0.0004213915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8273908,0.079376,0.003777911,0.0008413146,0.001169409,0.0001418177,0.000201654,0.002269608,0.02625975,0.000420686,0.004658824,0.05349234],"study_design_scores_gemma":[0.6036651,0.3843822,0.005236009,0.00003066879,0.0004016196,0.000208164,0.00004509004,0.0015415,0.002319373,0.0001919803,0.001953373,0.00002490933],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874621,0.001560118,0.0006390901,0.0005486425,0.0002072589,0.005314842,0.00172882,0.0001381834,0.002400872],"genre_scores_gemma":[0.9803861,0.00183863,0.002941801,0.001085709,0.0001802626,0.005587531,0.004192011,0.00005624098,0.003731808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006476722,"threshold_uncertainty_score":0.02166682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1050734302613676,"score_gpt":0.4624393885810661,"score_spread":0.3573659583196986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}