{"id":"W3126079253","doi":"10.20538/1682-0363-2020-4-80-85","title":"ABCA1 gene promoter methylation and sudden cardiac death","year":2021,"lang":"en","type":"article","venue":"Bulletin of Siberian Medicine","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Office of the Chief Medical Examiner","funders":"","keywords":"Methylation; Sudden death; Sudden cardiac death; Promoter; Gene; DNA methylation; Medicine; Polymerase chain reaction; Internal medicine; ABCA1; Pathological; Cardiology; Biology; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004561761,0.000218677,0.000295424,0.0005424155,0.0002171902,0.0001790269,0.0001350589,0.0002482706,0.001839189],"category_scores_gemma":[0.0007262494,0.0001311878,0.0001949196,0.0003635145,0.000172741,0.0001017109,0.0001682241,0.0002107194,0.0001439676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001217422,"about_ca_system_score_gemma":0.0001960076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008210306,"about_ca_topic_score_gemma":0.0006532186,"domain_scores_codex":[0.9998087,0.0000646732,0.000013805,0.00005635933,0.00003428023,0.00002207114],"domain_scores_gemma":[0.9996684,0.0001053512,0.000108243,0.00002073207,0.00003743732,0.00005996376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007108413,0.00008926421,0.9870778,0.00006853856,0.0001602653,0.000257899,0.0001238549,0.00006313243,0.003388266,0.00005158206,0.00009021829,0.007918162],"study_design_scores_gemma":[0.000008116258,0.0002336626,0.9983918,0.000005621126,0.00005740064,0.0006002997,0.00004854102,0.0001701444,0.0002869584,0.00003983112,0.0001554511,0.000002077],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986589,0.0008068349,0.000159986,0.00002658838,0.000007653517,0.000006939612,0.00009412555,0.000002946616,0.0002359551],"genre_scores_gemma":[0.9993746,0.0001941475,0.0001199981,0.000009898884,0.00001211124,0.000006442106,0.00009866204,7.089268e-7,0.0001834287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001839189,"threshold_uncertainty_score":0.006152689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01760685243357644,"score_gpt":0.2605292296020275,"score_spread":0.2429223771684511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}