{"id":"W3126261238","doi":"10.21203/rs.3.rs-17131/v1","title":"Elevated levels of miR-483-5p in oocytes aggravates premature ovarian insufficiency induced by CDDP by targeting the FKBP4","year":2020,"lang":"en","type":"preprint","venue":"","topic":"Birth, Development, and Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; Southern Medical University; Shenzhen University; National Natural Science Foundation of China","keywords":"Premature ovarian insufficiency; Premature ovarian failure; Andrology; microRNA; Ovarian cancer; Medicine; Internal medicine; Biology; Cancer; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001499592,0.0003455412,0.0005891546,0.0003490901,0.0002031174,0.0003251831,0.0002383776,0.0003863345,0.003258815],"category_scores_gemma":[0.0001511063,0.0001903803,0.0004180661,0.0002195285,0.0002694154,0.0002299463,0.0002158545,0.0008157091,0.0007232519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000327948,"about_ca_system_score_gemma":0.0002648078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005842583,"about_ca_topic_score_gemma":0.0008952137,"domain_scores_codex":[0.9997826,0.00001706073,0.00002654146,0.0000509696,0.00007193797,0.00005079651],"domain_scores_gemma":[0.9998938,0.0000115343,0.00004127147,0.00000757765,0.00001575324,0.0000300578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005111864,0.0000379669,0.0004852469,0.0002270793,0.0000171405,0.0001436271,0.00002396018,0.00006201868,0.9953048,0.0001040931,0.0004157498,0.002667241],"study_design_scores_gemma":[0.000107718,0.0007637116,0.01383071,0.00004003225,0.0001336328,0.000858375,0.00008002393,0.001434963,0.969946,0.0001587344,0.01262783,0.00001814929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9637839,0.01375112,0.01088425,0.0008370851,0.0004781727,0.0001832573,0.00396366,0.0009108761,0.005207758],"genre_scores_gemma":[0.9818139,0.004142195,0.004887781,0.0003629883,0.0000627948,0.0002145131,0.002096208,0.0001345083,0.006285157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003258815,"threshold_uncertainty_score":0.01090187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04087609991797931,"score_gpt":0.3017641360959691,"score_spread":0.2608880361779898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}